ProSci

Cysteine Dioxygenase Type 1 Recombinant Protein

Product Code:
 
PSI-91-984
Product Group:
 
Recombinant Proteins
Supplier:
 
ProSci
Regulatory Status:
 
RUO
Target Species:
 
Human
Storage:
 
Store at -20˚C, stable for 6 months after receipt.
Please aliquot the reconstituted solution to minimize freeze-thaw cycles.
 

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CodeSizePrice
PSI-91-984-0.05mg0.05mg£449.00
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Further Information

Additional Names:
Cysteine Dioxygenase Type 1, Cysteine Dioxygenase Type I, CDO, CDO-I, CDO1
Application Note:
This recombinant protein can be used for biological assays. For research use only.
Background:
Cysteine Dioxygenase Type 1 (CDO1) is a mammalian non-heme iron enzyme that belongs to the cysteine dioxygenase family. CDO1 is highly expressed in the liver and placenta, and has a low expression in heart, brain and pancreas. CDO1 can also be detected in hepatoblastoma HepG2 cells. CDO1 catalyzes the conversion of L-cysteine to cysteine sulfinic acid by incorporation of dioxygen. CDO1 is a vital regulator of cellular cysteine concentrations and has an essential role in maintaining the hepatic concentration of intracellular free cysteine within a proper narrow range. CDO1 is able to alter intracellular cysteine levels and glutathione levels.
Buffer:
Supplied as a 0.2 um filtered solution of 20mM TrisHCl, 1mM DTT, 10% Glycerol, pH 8.0. It is not recommended to reconstitute to a concentration less than 100 ug/ml.
Fusion Tag:
N-6 His tag
NCBI Gene ID #:
1036
NCBI Official Name:
cysteine dioxygenase type 1
NCBI Official Symbol:
CDO1
NCBI Organism:
Homo sapiens
Physical State:
Liquid
Predicted Molecular Weight:
25.1 kD
Protein Accession #:
Q16878
Protein GI Number:
767928039
Purity:
Greater than 95% as determined by reducing SDS-PAGE.
Endotoxin level less than 0.1 ng/ug (1 IEU/ug) as determined by LAL test.
Recombinant Protein Sequence:
Thr32-Gly402
Source:
E. coli
Swissprot #:
Q16878

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