No additional charges, what you see is what you pay! *
Stay in control of your spending. These prices have no additional charges, not even shipping!
* Rare exceptions are clearly labelled (only 0.14% of items!).
Multibuy discounts available!
Contact us to find what you can save.
This product comes from:
Switzerland.
Typical lead time:
7-10 working days.
Contact us for more accurate information.
- Further Information
- Documents
- References
- Show All
Further Information
Alternate Names/Synonyms:
IC-87114
Solid.
371242-69-2
32160000
liquid
GHS07
H303, H317, H333
InChI=1S/C22H19N7O/c1-13-6-3-4-9-16(13)29-17(27-15-8-5-7-14(2)18(15)22(29)30)10-28-12-26-19-20(23)24-11-25-21(19)28/h3-9,11-12H,10H2,1-2H3,(H2,23,24,25)
GNWHRHGTIBRNSM-UHFFFAOYSA-N
Chemical. CAS: 371242-69-2. Formula: C22H19N7O. MW: 397.4. IC87114 is a potent, ATP-competitive, and selective inhibitor of PI3Kdelta. IC(50) values (130-500nM) for IC87114 are sub-micromolar over a wide range of ATP concentrations from 10µM to 200µM. IC87114 can selectively inhibit cellular migration but not adhesion as well as cellular polarization. More recent work has shown the PIK3delta inhibition also plays a role in autoimmune disease suppression.
C22H19N7O
397.4
Plastic Vial
P261, P272, P280, P302, P352, P333, P313, P321, P363, P501
IC87114 is a potent, ATP-competitive, and selective inhibitor of PI3Kdelta. IC(50) values (130-500nM) for IC87114 are sub-micromolar over a wide range of ATP concentrations from 10µM to 200µM. IC87114 can selectively inhibit cellular migration but not adhesion as well as cellular polarization. More recent work has shown the PIK3delta inhibition also plays a role in autoimmune disease suppression.
>95%
Warning
Soluble in DMSO. Slightly soluble (<1mg/ml) in ethanol.
Non-hazardous
Protein Kinase Modulators
12352200
Stable for at least 2 years after receipt when stored at -20°C.
