AdipoGen Life Sciences

AS-252424

Product Code:
 
SYN-1009
Product Group:
 
Inhibitors and Activators
Regulatory Status:
 
RUO
Shipping:
 
-20°C
1 / 1
Chemical Structure
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Chemical Structure

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SYN-1009-M100100 mgEnquire
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Further Information

Alternate Names/Synonyms:
AS252424
Appearance:
Solid.
CAS:
900515-16-4
EClass:
32160000
Form (Short):
liquid
GHS Symbol:
GHS07
Hazards:
H303, H317, H333
InChi:
InChI=1S/C14H8FNO4S/c15-7-1-3-9(10(17)5-7)11-4-2-8(20-11)6-12-13(18)16-14(19)21-12/h1-6,17H,(H,16,18,19)/b12-6-
InChiKey:
OYYVWNDMOQPMGE-SDQBBNPISA-N
Long Description:
Chemical. CAS: 900515-16-4. Formula: C14H8FNO4S. MW: 305.3. AS-252424 is a potent and selective PI3K inhibitor. It inhibits human recombinant PI3K alpha, beta, gamma and delta with IC(50) values of 30, 940, 20,000, and 20,000nM respectively.
Molecular Formula:
C14H8FNO4S
Molecular Weight:
305.3
Package Type:
Plastic Vial
Precautions:
P280, P301, P312, P304, P312, P302, P352, P333, P313
Product Description:
AS-252424 is a potent and selective PI3K inhibitor. It inhibits human recombinant PI3K alpha, beta, gamma and delta with IC(50) values of 30, 940, 20,000, and 20,000nM respectively.
Purity:
>95%
Signal word:
Warning
Solubility Chemicals:
Soluble in DMSO. Slightly soluble (<1mg/ml) in ethanol.
Transportation:
Non-hazardous
UNSPSC Category:
Protein Kinase Modulators
UNSPSC Number:
12352200
Use & Stability:
Stable for at least 2 years after receipt when stored at -20°C.

References

Furan-2-ylmethylene thiazolidinediones as novel, potent, and selective inhibitors of phosphoinositide 3-kinase gamma: V. Pomel, et al.; J. Med. Chem. 49, 3857 (2006)