Further Information
Alternate Names/Synonyms:
BAY-73-4506
Solid.
755037-03-7
32160000
liquid
InChI=1S/C21H15ClF4N4O3/c1-27-19(31)18-10-13(6-7-28-18)33-12-3-5-17(16(23)9-12)30-20(32)29-11-2-4-15(22)14(8-11)21(24,25)26/h2-10H,1H3,(H,27,31)(H2,29,30,32)
FNHKPVJBJVTLMP-UHFFFAOYSA-N
Chemical. CAS: 755037-03-7. Formula: C21H15ClF4N4O3. MW: 482.8. Regorafenib (BAY 73-4506, Fluoro-Sorafenib) is a multi-target inhibitor for VEGFR1, VEGFR2, VEGFR3, PDGFR, Kit, RET and Raf-1 with IC(50) values of 13, 4.2, 46, 22, 7, 1.5 and 2.5nM, respectively.
C21H15ClF4N4O3
482.8
Plastic Vial
Regorafenib (BAY 73-4506, Fluoro-Sorafenib) is a multi-target inhibitor for VEGFR1, VEGFR2, VEGFR3, PDGFR, Kit, RET and Raf-1 with IC(50) values of 13, 4.2, 46, 22, 7, 1.5 and 2.5nM, respectively.
>95%
Soluble in DMSO or ethanol.
Non-hazardous
Protein Kinase Modulators
12352200
Stable for at least 2 years after receipt when stored at -20°C.