Further Information
Alternate Names/Synonyms:
Bayer18
Solid.
1251752-12-1
32160000
liquid
GHS07
H302, H317
InChI=1S/C19H27FN6O2/c1-18(2,3)26-17(28)23-13-8-6-7-12(9-13)22-16-21-10-14(20)15(24-16)25-19(4,5)11-27/h6-10,27H,11H2,1-5H3,(H2,23,26,28)(H2,21,22,24,25)
DYNMZYFOSRSMAC-UHFFFAOYSA-N
Chemical. CAS: 1251752-12-1. Formula: C19H27FN6O2. MW: 390.5. Bayer-18 is a selective TYK2 inhibitor, with an IC(50) of 18.7nM on TYK2 as measured by TYK2 HTRF assays. The compound shows 1000 fold selectivity against JAK2, CDK and KDR kinases in similar HTRF assays.
C19H27FN6O2
390.5
Plastic Vial
P264, P270, P301, P312, P330, P501, P261, P272, P280, P302, P352, P333, P313, P321, P363, P501
Bayer-18 is a selective TYK2 inhibitor, with an IC(50) of 18.7nM on TYK2 as measured by TYK2 HTRF assays. The compound shows 1000 fold selectivity against JAK2, CDK and KDR kinases in similar HTRF assays.
>95%
Warning
Soluble in DMSO.
Non-hazardous
Protein Kinase Modulators
12352200
Stable for at least 2 years after receipt when stored at -20°C.