AdipoGen Life Sciences

AG-13958

Product Code:
 
SYN-1004
Product Group:
 
Inhibitors and Activators
Regulatory Status:
 
RUO
Shipping:
 
-20°C
1 / 1
Chemical Structure
❮❯

Chemical Structure

No additional charges, what you see is what you pay! *

CodeSizePrice
SYN-1004-M100100 mgEnquire
Quantity:
SYN-1004-M05050 mgEnquire
Quantity:
SYN-1004-M0011 mg£303.00
Quantity:
SYN-1004-M0055 mg£590.00
Quantity:
SYN-1004-M01010 mg£900.00
Quantity:
Prices exclude any Taxes / VAT
How to order with us   Contact us
Stay in control of your spending. These prices have no additional charges, not even shipping!
* Rare exceptions are clearly labelled (only 0.14% of items!).
Multibuy discounts available! Contact us to find what you can save.
This product comes from: Switzerland.
Typical lead time: 7-10 working days.
Contact us for more accurate information.
  • Further Information
  • Documents
  • References
  • Show All

Further Information

Alternate Names/Synonyms:
AG-13958
Appearance:
Solid.
CAS:
319460-94-1
EClass:
32160000
Form (Short):
liquid
InChi:
InChI=1S/C26H22FN7O/c1-16-15-29-34(2)25(16)26(35)31-24-14-19(7-10-21(24)27)30-18-6-9-20-22(32-33-23(20)13-18)11-8-17-5-3-4-12-28-17/h3-15,30H,1-2H3,(H,31,35)(H,32,33)/b11-8+
InChiKey:
LLMBCXVXEQNNJB-DHZHZOJOSA-N
Long Description:
Chemical. CAS: 319460-94-1. Formula: C26H22FN7O. MW: 467.5. AG13958 is a VEGF inhibitor that was in clinical development for treatment of age-related macular degeneration (AMD). The drug displays low water solubility and so far in trials delivery has been difficult needing direct injection to be truly effective and it varied by the species used because of species specific differences in eye circulation and vascularization. As a VEGF inhibitor AG13958 was targeted to FLT/TYK receptor inhibition.
Molecular Formula:
C26H22FN7O
Molecular Weight:
467.5
Package Type:
Plastic Vial
Product Description:
AG13958 is a VEGF inhibitor that was in clinical development for treatment of age-related macular degeneration (AMD). The drug displays low water solubility and so far in trials delivery has been difficult needing direct injection to be truly effective and it varied by the species used because of species specific differences in eye circulation and vascularization. As a VEGF inhibitor AG13958 was targeted to FLT/TYK receptor inhibition.
Purity:
>95%
Solubility Chemicals:
Soluble in DMSO.
Transportation:
Non-hazardous
UNSPSC Category:
Protein Kinase Modulators
UNSPSC Number:
12352200
Use & Stability:
Stable for at least 2 years after receipt when stored at -20°C.

References

2nd Ophthalmic Drug Development and Delivery Summit: M. Marra, et al.; Expert Opin. Drug Deliv. 4, 77 (2007)