Further Information
Epithelial cell adhesion molecule, Ep-CAM, Adenocarcinoma-associated antigen, Cell surface glycoprotein Trop-1, Epithelial cell surface antigen, Epithelial glycoprotein, EGP, Epithelial glycoprotein 314, EGP314, hEGP314, KS 1/4 antigen, KSA, Major gastrointestinal tumor-associated protein GA733-2, Tumor-associated calcium signal transducer 1, CD326, EPCAM, GA733-2, M1S2, M4S1, MIC18, TACSTD1, TROP1
For WB starting dilution is: 1:1000
This gene encodes a carcinoma-associated antigen and is a
member of a family that includes at least two type I membrane
proteins. This antigen is expressed on most normal epithelial cells
and gastrointestinal carcinomas and functions as a homotypic
calcium-independent cell adhesion molecule. The antigen is being
used as a target for immunotherapy treatment of human carcinomas.
Mutations in this gene result in congenital tufting enteropathy.
- Kimura, O., et al. Cancer Sci. 101(10):2145-2155(2010)
- Jiang, L., et al. Breast Cancer Res. Treat. (2010) In press :
- Lugli, A., et al. Br. J. Cancer 103(3):382-390(2010)
- Johnatty, S.E., et al. PLoS Genet.(7), E1001016 (2010) :
Supplied in PBS with 0.09% (W/V) sodium azide.
batch dependent
Unconjugated
Optimal dilutions/concentrations should be determined by the end user. The information provided is a guideline for product use. This product is for research use only.
This EpCAM antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 200-229 amino acids from the C-terminal region of human EpCAM.
4072
Epithelial cell adhesion molecule
EPCAM
Homo sapiens
Liquid
PREDICTED MOLECULAR WEIGHT:
35 kDa
P16422
160266056
This antibody is purified through a protein A column, followed by peptide affinity purification.
Cancer,Cell Cycle,Signal Transduction
P16422
Optimal dilutions for each application to be determined by the researcher.