ProSci

Msx2 Antibody

Product Code:
 
PSI-61-435
Product Group:
 
Primary Antibodies
Supplier:
 
ProSci
Host Type:
 
Rabbit
Antibody Isotype:
 
Rabbit Ig
Antibody Clonality:
 
Polyclonal
Regulatory Status:
 
RUO
Target Species:
 
Human
Applications:
  • Immunohistochemistry- Paraffin Embedded (IHC-P)
  • Western Blot (WB)
Storage:
 
Store at 4˚C for three months and -20˚C, stable for up to one year. As with all antibodies care should be taken to avoid repeated freeze thaw cycles. Antibodies should not be exposed to prolonged high temperatures.
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Western blot analysis of Msx2 using rabbit polyclonal Msx2 Antibody (Human C-term) using 293 cell lysates (2 ug/lane) either nontransfected (Lane 1) or transiently transfected with the Msx2 gene (Lane 2).
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Formalin-fixed and paraffin-embedded human breast carcinoma tissue reacted with Msx2 Antibody , which was peroxidase-conjugated to the secondary antibody, followed by DAB staining.
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Western blot analysis of Msx2 using rabbit polyclonal Msx2 Antibody (Human C-term) using 293 cell lysates (2 ug/lane) either nontransfected (Lane 1) or transiently transfected with the Msx2 gene (Lane 2).
Formalin-fixed and paraffin-embedded human breast carcinoma tissue reacted with Msx2 Antibody , which was peroxidase-conjugated to the secondary antibody, followed by DAB staining.

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PSI-61-435-400ul400ul£626.00
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Further Information

Additional Names:
Homeobox protein MSX-2, Homeobox protein Hox-8, MSX2, HOX8
Application Note:
For WB starting dilution is: 1:1000

For IHC-P starting dilution is: 1:10~50
Background:
This gene encodes a member of the muscle segment homeobox gene family. The encoded protein is a transcriptional repressor whose normal activity may establish a balance between survival and apoptosis of neural crest-derived cells required for proper craniofacial morphogenesis. The encoded protein may also have a role in promoting cell growth under certain conditions and may be an important target for the RAS signaling pathways. Mutations in this gene are associated with parietal foramina 1 and craniosynostosis type 2.
Background References:
  • Shao,J.S., Ann. N. Y. Acad. Sci. 1117, 40-50 (2007)
  • Han,J., Mech. Dev. 124 (9-10), 729-745 (2007)
  • Ghassibe,M., Eur. J. Pediatr. 165 (10), 734-735 (2006)
Buffer:
Supplied in PBS with 0.09% (W/V) sodium azide.
Concentration:
batch dependent
Conjugate:
Unconjugated
DISCLAIMER:
Optimal dilutions/concentrations should be determined by the end user. The information provided is a guideline for product use. This product is for research use only.
Immunogen:
This Msx2 antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 191-222 amino acids from the C-terminal region of human Msx2.
NCBI Gene ID #:
4488
NCBI Official Name:
Homeobox protein MSX-2
NCBI Official Symbol:
MSX2
NCBI Organism:
Homo sapiens
Physical State:
Liquid
PREDICTED MOLECULAR WEIGHT:
29 kDa
Protein Accession #:
P35548
Protein GI Number:
311033429
Purification:
This antibody is purified through a protein A column, followed by peptide affinity purification.
Research Area:
Cancer,Neuroscience
Swissprot #:
P35548
User NOte:
Optimal dilutions for each application to be determined by the researcher.