ProSci

KBTBD10 Antibody

Product Code:
 
PSI-58-492
Product Group:
 
Primary Antibodies
Supplier:
 
ProSci
Host Type:
 
Rabbit
Antibody Isotype:
 
Rabbit Ig
Antibody Clonality:
 
Polyclonal
Regulatory Status:
 
RUO
Target Species:
 
Human
Application:
 
Western Blot (WB)
Storage:
 
Store at 4˚C for three months and -20˚C, stable for up to one year. As with all antibodies care should be taken to avoid repeated freeze thaw cycles. Antibodies should not be exposed to prolonged high temperatures.
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Western blot analysis in NCI-H292 cell line lysates (35ug/lane).
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Western blot analysis in NCI-H292 cell line lysates (35ug/lane).

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PSI-58-492-400ul400ul£626.00
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Further Information

Additional Names:
Kelch-like protein 41, Kel-like protein 23, Kelch repeat and BTB domain-containing protein 10, Kelch-related protein 1, Sarcosin, KLHL41, KBTBD10, KRP1
Application Note:
For WB starting dilution is: 1:1000
Background:
KBTBD10 is required for pseudopod elongation in transformed cells. Substrate-specific adapter of an E3 ubiquitin-protein ligase complex which mediates the ubiquitination and subsequent proteasomal degradation of target proteins.
Background References:
  • Foster, L.J., et al. J. Proteome Res. 5(1):64-75(2006)
  • Lim, D.S., et al. J. Am. Coll. Cardiol. 38(4):1175-1180(2001)
  • Spence, H.J., et al. Oncogene 19(10):1266-1276(2000)
  • Taylor, A., et al. Mol. Cell. Biochem. 183 (1-2), 105-112 (1998) :
Buffer:
Supplied in PBS with 0.09% (W/V) sodium azide.
Concentration:
batch dependent
Conjugate:
Unconjugated
DISCLAIMER:
Optimal dilutions/concentrations should be determined by the end user. The information provided is a guideline for product use. This product is for research use only.
Homology:
Predicted species reactivity based on immunogen sequence: Mouse, Rat
Immunogen:
This KBTBD10 antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 547-575 amino acids from the C-terminal region of human KBTBD10.
NCBI Gene ID #:
10324
NCBI Official Name:
Kelch-like protein 41
NCBI Official Symbol:
KLHL41
NCBI Organism:
Homo sapiens
Physical State:
Liquid
PREDICTED MOLECULAR WEIGHT:
68 kDa
Protein Accession #:
O60662
Purification:
This antibody is purified through a protein A column, followed by peptide affinity purification.
Research Area:
Cell Cycle
Swissprot #:
O60662
User NOte:
Optimal dilutions for each application to be determined by the researcher.