ProSci

PDS5B Antibody

Product Code:
 
PSI-61-175
Product Group:
 
Primary Antibodies
Supplier:
 
ProSci
Host Type:
 
Rabbit
Antibody Isotype:
 
Rabbit Ig
Antibody Clonality:
 
Polyclonal
Regulatory Status:
 
RUO
Target Species:
 
Human
Application:
 
Western Blot (WB)
Storage:
 
Store at 4˚C for three months and -20˚C, stable for up to one year. As with all antibodies care should be taken to avoid repeated freeze thaw cycles. Antibodies should not be exposed to prolonged high temperatures.
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Western Blot at 1:2000 dilution Lane 1: 293T/17 whole cell lysate Lane 2: DU145 whole cell lysate Lane 3: LNCaP whole cell lysate Lane 4: Raji whole cell lysate Lane 5: U-2OS whole cell lysate Lane 6: Hela whole cell lysate Lysates/proteins at 20 ug per lane.
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Western Blot at 1:2000 dilution Lane 1: 293T/17 whole cell lysate Lane 2: DU145 whole cell lysate Lane 3: LNCaP whole cell lysate Lane 4: Raji whole cell lysate Lane 5: U-2OS whole cell lysate Lane 6: Hela whole cell lysate Lysates/proteins at 20 ug per lane.

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PSI-61-175-200ul200ul£626.00
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Further Information

Additional Names:
Sister chromatid cohesion protein PDS5 homolog B, Androgen-induced proliferation inhibitor, Androgen-induced prostate proliferative shutoff-associated protein AS3, PDS5B
Application Note:
For WB starting dilution is: 1:2000
Background:
Regulator of sister chromatid cohesion in mitosis which may stabilize cohesin complex association with chromatin. May couple sister chromatid cohesion during mitosis to DNA replication. Cohesion ensures that chromosome partitioning is accurate in both meiotic and mitotic cells and plays an important role in DNA repair. Plays a role in androgen-induced proliferative arrest in prostate cells.
Background References:
  • Geck P.,et al.J. Steroid Biochem. Mol. Biol. 63:211-218(1997).
  • Geck P.,et al.J. Steroid Biochem. Mol. Biol. 68:41-50(1999).
  • Nagase T.,et al.DNA Res. 6:63-70(1999).
  • Nakajima D.,et al.DNA Res. 9:99-106(2002).
Buffer:
Supplied in PBS with 0.09% (W/V) sodium azide.
Concentration:
batch dependent
Conjugate:
Unconjugated
DISCLAIMER:
Optimal dilutions/concentrations should be determined by the end user. The information provided is a guideline for product use. This product is for research use only.
Immunogen:
This PDS5B antibody is generated from a rabbit immunized with a KLH conjugated synthetic peptide between 1197-1228 amino acids from human PDS5B.
NCBI Gene ID #:
23047
NCBI Official Name:
Sister chromatid cohesion protein PDS5 homolog B
NCBI Official Symbol:
PDS5B
NCBI Organism:
Homo sapiens
Physical State:
Liquid
PREDICTED MOLECULAR WEIGHT:
165 kDa
Protein Accession #:
Q9NTI5
Protein GI Number:
74725312
Purification:
This antibody is purified through a protein A column, followed by peptide affinity purification.
Research Area:
Cell Cycle
Swissprot #:
Q9NTI5
User NOte:
Optimal dilutions for each application to be determined by the researcher.