ProSci

DCC1 Antibody

Product Code:
 
PSI-61-568
Product Group:
 
Primary Antibodies
Supplier:
 
ProSci
Host Type:
 
Rabbit
Antibody Isotype:
 
Rabbit Ig
Antibody Clonality:
 
Polyclonal
Regulatory Status:
 
RUO
Target Species:
 
Human
Application:
 
Western Blot (WB)
Storage:
 
Store at 4˚C for three months and -20˚C, stable for up to one year. As with all antibodies care should be taken to avoid repeated freeze thaw cycles. Antibodies should not be exposed to prolonged high temperatures.
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Western blot analysis in CEM cell line lysates (35ug/lane).
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Western blot analysis in CEM cell line lysates (35ug/lane).

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PSI-61-568-400ul400ul£626.00
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Further Information

Additional Names:
Sister chromatid cohesion protein DCC1, Defective in sister chromatid cohesion protein 1 homolog, DSCC1, DCC1
Application Note:
For WB starting dilution is: 1:1000
Background:
CHTF18 (MIM 613201), CHTF8 (MIM 613202), and DSCC1 are components of an alternative replication factor C (RFC) (see MIM 600404) complex that loads PCNA (MIM 176740) onto DNA during S phase of the cell cycle (Merkle et al., 2003 [PubMed 12766176]; Bermudez et al., 2003 [PubMed 12930902]).
Background References:
  • Murakami, T., et al. J. Biol. Chem. 285(45):34608-34615(2010)
  • Terret, M.E., et al. Nature 462(7270):231-234(2009)
  • Watrin, E., et al. Curr. Biol. 16(9):863-874(2006)
  • Bermudez, V.P., et al. Proc. Natl. Acad. Sci. U.S.A. 100(18):10237-10242(2003)
Buffer:
Supplied in PBS with 0.09% (W/V) sodium azide.
Concentration:
batch dependent
Conjugate:
Unconjugated
DISCLAIMER:
Optimal dilutions/concentrations should be determined by the end user. The information provided is a guideline for product use. This product is for research use only.
Immunogen:
This DCC1 antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 311-339 amino acids from the C-terminal region of human DCC1.
NCBI Gene ID #:
79075
NCBI Official Name:
Sister chromatid cohesion protein DCC1
NCBI Official Symbol:
DSCC1
NCBI Organism:
Homo sapiens
Physical State:
Liquid
PREDICTED MOLECULAR WEIGHT:
45 kDa
Protein Accession #:
Q9BVC3
Protein GI Number:
167012058
Purification:
This antibody is purified through a protein A column, followed by peptide affinity purification.
Research Area:
Cell Cycle
Swissprot #:
Q9BVC3
User NOte:
Optimal dilutions for each application to be determined by the researcher.