ProSci

PPIC Antibody

Product Code:
 
PSI-63-908
Product Group:
 
Primary Antibodies
Supplier:
 
ProSci
Host Type:
 
Rabbit
Antibody Isotype:
 
Rabbit Ig
Antibody Clonality:
 
Polyclonal
Regulatory Status:
 
RUO
Target Species:
 
Human
Applications:
  • Fluorescence-activated cell sorting (FACS)
  • Immunohistochemistry- Paraffin Embedded (IHC-P)
  • Western Blot (WB)
Storage:
 
Store at 4˚C for three months and -20˚C, stable for up to one year. As with all antibodies care should be taken to avoid repeated freeze thaw cycles. Antibodies should not be exposed to prolonged high temperatures.
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Western blot analysis of PPIC Antibody in Hela cell line lysates (35ug/lane)
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Formalin-fixed and paraffin-embedded human brain tissue reacted with PPIC Antibody , which was peroxidase-conjugated to the secondary antibody, followed by DAB staining.
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❮❯

Western blot analysis of PPIC Antibody in Hela cell line lysates (35ug/lane)
Formalin-fixed and paraffin-embedded human brain tissue reacted with PPIC Antibody , which was peroxidase-conjugated to the secondary antibody, followed by DAB staining.

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PSI-63-908-400ul400ul£626.00
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Further Information

Additional Names:
Peptidyl-prolyl cis-trans isomerase C, PPIase C, Cyclophilin C, Rotamase C, PPIC, CYPC
Application Note:
For WB starting dilution is: 1:1000

For IHC-P starting dilution is: 1:50~100

For FACS starting dilution is: 1:10~50
Background:
PPIC is a member of the peptidyl-prolyl cis-trans isomerase (PPIase)) family. PPIases catalyze the cis-trans isomerization of proline imidic peptide bonds in oligopeptides and accelerate the folding of proteins. Similar to other PPIases, this protein can bind immunosuppressant cyclosporin A.
Background References:
  • Vasan,R.S. JAMA 302 (2), 168-178 (2009)
  • Lim,J. Cell 125 (4), 801-814 (2006)
  • Trahey,M. Proc. Natl. Acad. Sci. U.S.A. 96 (6), 3006-3011 (1999)
Buffer:
Supplied in PBS with 0.09% (W/V) sodium azide.
Concentration:
batch dependent
Conjugate:
Unconjugated
DISCLAIMER:
Optimal dilutions/concentrations should be determined by the end user. The information provided is a guideline for product use. This product is for research use only.
Homology:
Predicted species reactivity based on immunogen sequence: Bovine
Immunogen:
This PPIC antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 61-89 amino acids from the Central region of human PPIC.
NCBI Gene ID #:
5480
NCBI Official Name:
Peptidyl-prolyl cis-trans isomerase C
NCBI Official Symbol:
PPIC
NCBI Organism:
Homo sapiens
Physical State:
Liquid
PREDICTED MOLECULAR WEIGHT:
23 kDa
Protein Accession #:
P45877
Protein GI Number:
1169178
Purification:
This antibody is purified through a protein A column, followed by peptide affinity purification.
Research Area:
Immunology,Signal Transduction
Swissprot #:
P45877
User NOte:
Optimal dilutions for each application to be determined by the researcher.