ProSci

KLF1 Antibody

Product Code:
 
PSI-57-769
Product Group:
 
Primary Antibodies
Supplier:
 
ProSci
Host Type:
 
Rabbit
Antibody Isotype:
 
Rabbit Ig
Antibody Clonality:
 
Polyclonal
Regulatory Status:
 
RUO
Target Species:
 
Human
Application:
 
Western Blot (WB)
Storage:
 
Store at 4˚C for three months and -20˚C, stable for up to one year. As with all antibodies care should be taken to avoid repeated freeze thaw cycles. Antibodies should not be exposed to prolonged high temperatures.
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Western blot analysis in NCI-H292 cell line lysates (35ug/lane).
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Western blot analysis in NCI-H292 cell line lysates (35ug/lane).

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PSI-57-769-400ul400ul£626.00
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Further Information

Additional Names:
Krueppel-like factor 1, Erythroid krueppel-like transcription factor, EKLF, KLF1, EKLF
Application Note:
For WB starting dilution is: 1:1000
Background:
This gene encodes a hematopoietic-specific transcription factor that induces high-level expression of adult beta-globin and other erythroid genes. The zinc-finger protein binds to the DNA sequence CCACACCCT found in the beta hemoglobin promoter. Heterozygous loss-of-function mutations in this gene result in the dominant In(Lu) blood phenotype.
Background References:
  • Borg, J., et al. Nat. Genet. 42(9):801-805(2010)
  • Zhou, D., et al. Nat. Genet. 42(9):742-744(2010)
  • Rose, J.E., et al. Mol. Med. 16 (7-8), 247-253 (2010) :
  • Papachatzopoulou, A., et al. Hemoglobin 34(4):333-342(2010)
Buffer:
Supplied in PBS with 0.09% (W/V) sodium azide.
Concentration:
batch dependent
Conjugate:
Unconjugated
DISCLAIMER:
Optimal dilutions/concentrations should be determined by the end user. The information provided is a guideline for product use. This product is for research use only.
Immunogen:
This KLF1 antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 248-276 amino acids from the C-terminal region of human KLF1.
NCBI Gene ID #:
10661
NCBI Official Name:
Krueppel-like factor 1
NCBI Official Symbol:
KLF1
NCBI Organism:
Homo sapiens
Physical State:
Liquid
PREDICTED MOLECULAR WEIGHT:
38 kDa
Protein Accession #:
Q13351
Protein GI Number:
2501699
Purification:
This antibody is purified through a protein A column, followed by peptide affinity purification.
Research Area:
Neuroscience
Swissprot #:
Q13351
User NOte:
Optimal dilutions for each application to be determined by the researcher.