ProSci

NAB2 Antibody

Product Code:
 
PSI-63-078
Product Group:
 
Primary Antibodies
Supplier:
 
ProSci
Host Type:
 
Rabbit
Antibody Isotype:
 
Rabbit Ig
Antibody Clonality:
 
Polyclonal
Regulatory Status:
 
RUO
Target Species:
 
Human
Application:
 
Western Blot (WB)
Storage:
 
Store at 4˚C for three months and -20˚C, stable for up to one year. As with all antibodies care should be taken to avoid repeated freeze thaw cycles. Antibodies should not be exposed to prolonged high temperatures.
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Western blot analysis of NAB2 antibody in A375 cell line lysates (35ug/lane)
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Western blot analysis of NAB2 antibody in A375 cell line lysates (35ug/lane)

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PSI-63-078-400ul400ul£626.00
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Further Information

Additional Names:
NGFI-A-binding protein 2, EGR-1-binding protein 2, Melanoma-associated delayed early response protein, Protein MADER, NAB2, MADER
Application Note:
For WB starting dilution is: 1:1000
Background:
NAB2 is a member of the family of NGFI-A binding (NAB) proteins, which function in the nucleus to repress transcription induced by some members of the EGR (early growth response) family of transactivators. NAB proteins can homo- or hetero-multimerize with other EGR or NAB proteins through a conserved N-terminal domain, and repress transcription through two partially redundant C-terminal domains. Transcriptional repression by this protein is mediated in part by interactions with the nucleosome remodeling and deactylase (NuRD) complex.
Background References:
  • Srinivasan,R., J. Biol. Chem. 281 (22), 15129-15137 (2006)
  • Kumbrink,J., J. Biol. Chem. 280 (52), 42785-42793 (2005)
  • Lucerna,M., J. Biol. Chem. 278 (13), 11433-11440 (2003)
Buffer:
Supplied in PBS with 0.09% (W/V) sodium azide.
Concentration:
batch dependent
Conjugate:
Unconjugated
DISCLAIMER:
Optimal dilutions/concentrations should be determined by the end user. The information provided is a guideline for product use. This product is for research use only.
Homology:
Predicted species reactivity based on immunogen sequence: Mouse
Immunogen:
This NAB2 antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 109-138 amino acids from the Central region of human NAB2.
NCBI Gene ID #:
4665
NCBI Official Name:
NGFI-A-binding protein 2
NCBI Official Symbol:
NAB2
NCBI Organism:
Homo sapiens
Physical State:
Liquid
PREDICTED MOLECULAR WEIGHT:
57 kDa
Protein Accession #:
Q15742
Protein GI Number:
12643729
Purification:
This antibody is prepared by Saturated Ammonium Sulfate (SAS) precipitation followed by dialysis
Research Area:
Neuroscience
Swissprot #:
Q15742
User NOte:
Optimal dilutions for each application to be determined by the researcher.