ProSci

CACNB3 Antibody

Product Code:
 
PSI-59-240
Product Group:
 
Primary Antibodies
Supplier:
 
ProSci
Host Type:
 
Rabbit
Antibody Isotype:
 
Rabbit Ig
Antibody Clonality:
 
Polyclonal
Regulatory Status:
 
RUO
Target Species:
 
Human
Application:
 
Western Blot (WB)
Storage:
 
Store at 4˚C for three months and -20˚C, stable for up to one year. As with all antibodies care should be taken to avoid repeated freeze thaw cycles. Antibodies should not be exposed to prolonged high temperatures.
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Western blot analysis in 293 cell line lysates (35ug/lane).
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Western blot analysis in 293 cell line lysates (35ug/lane).

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PSI-59-240-400ul400ul£626.00
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Further Information

Additional Names:
Voltage-dependent L-type calcium channel subunit beta-3, CAB3, Calcium channel voltage-dependent subunit beta 3, CACNB3, CACNLB3
Application Note:
For WB starting dilution is: 1:1000
Background:
The beta subunit of voltage-dependent calcium channels contributes to the function of the calcium channel by increasing peak calcium current, shifting the voltage dependencies of activation and inactivation, modulating G protein inhibition and controlling the alpha-1 subunit membrane targeting.
Background References:
  • Zhang, Y., et al. J. Biol. Chem. 285(4):2527-2536(2010)
  • Bernardo, J.F., et al. Can. J. Physiol. Pharmacol. 87(7):522-530(2009)
  • Voss, M., et al. BMC Immunol. 10, 53 (2009) :
  • Rikova, K., et al. Cell 131(6):1190-1203(2007)
Buffer:
Supplied in PBS with 0.09% (W/V) sodium azide.
Concentration:
batch dependent
Conjugate:
Unconjugated
DISCLAIMER:
Optimal dilutions/concentrations should be determined by the end user. The information provided is a guideline for product use. This product is for research use only.
Homology:
Predicted species reactivity based on immunogen sequence: Mouse, Rabbit, Rat
Immunogen:
This CACNB3 antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 407-434 amino acids from the C-terminal region of human CACNB3.
NCBI Gene ID #:
784
NCBI Official Name:
Voltage-dependent L-type calcium channel subunit beta-3
NCBI Official Symbol:
CACNB3
NCBI Organism:
Homo sapiens
Physical State:
Liquid
PREDICTED MOLECULAR WEIGHT:
55 kDa
Protein Accession #:
P54284
Protein GI Number:
1705683
Purification:
This antibody is purified through a protein A column, followed by peptide affinity purification.
Research Area:
Neuroscience
Swissprot #:
P54284
User NOte:
Optimal dilutions for each application to be determined by the researcher.