ProSci

TBCE Antibody

Product Code:
 
PSI-64-058
Product Group:
 
Primary Antibodies
Supplier:
 
ProSci
Host Type:
 
Rabbit
Antibody Isotype:
 
Rabbit Ig
Antibody Clonality:
 
Polyclonal
Regulatory Status:
 
RUO
Target Species:
 
Human
Application:
 
Western Blot (WB)
Storage:
 
Store at 4˚C for three months and -20˚C, stable for up to one year. As with all antibodies care should be taken to avoid repeated freeze thaw cycles. Antibodies should not be exposed to prolonged high temperatures.
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Western blot analysis in CEM,K562 cell line lysates (35ug/lane).
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Western blot analysis in CEM,K562 cell line lysates (35ug/lane).

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PSI-64-058-400ul400ul£626.00
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Further Information

Additional Names:
Tubulin-specific chaperone E, Tubulin-folding cofactor E, TBCE
Application Note:
For WB starting dilution is: 1:1000
Background:
Cofactor E is one of four proteins (cofactors A, D, E, and C) involved in the pathway leading to correctly folded beta-tubulin from folding intermediates. Cofactors A and D are believed to play a role in capturing and stabilizing beta-tubulin intermediates in a quasi-native confirmation. Cofactor E binds to the cofactor D/beta-tubulin complex; interaction with cofactor C then causes the release of beta-tubulin polypeptides that are committed to the native state.
Background References:
  • Biernacki, M.A., et al. Cancer Res. 70(3):906-915(2010)
  • Padidela, R., et al. J. Clin. Endocrinol. Metab. 94(8):2686-2691(2009)
  • Lindgren, C.M., et al. PLoS Genet.(6), E1000508 (2009)
  • Jin, S., et al. Development 136(9):1571-1581(2009)
Buffer:
Supplied in PBS with 0.09% (W/V) sodium azide.
Concentration:
batch dependent
Conjugate:
Unconjugated
DISCLAIMER:
Optimal dilutions/concentrations should be determined by the end user. The information provided is a guideline for product use. This product is for research use only.
Immunogen:
This TBCE antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 364-392 amino acids from the Central region of human TBCE.
NCBI Gene ID #:
6905
NCBI Official Name:
Tubulin-specific chaperone E
NCBI Official Symbol:
TBCE
NCBI Organism:
Homo sapiens
Physical State:
Liquid
PREDICTED MOLECULAR WEIGHT:
59 kDa
Protein Accession #:
Q15813
Protein GI Number:
74762146
Purification:
This antibody is purified through a protein A column, followed by peptide affinity purification.
Research Area:
Neuroscience,Signal Transduction
Swissprot #:
Q15813
User NOte:
Optimal dilutions for each application to be determined by the researcher.