ProSci

MTMR14 Antibody

Product Code:
 
PSI-59-225
Product Group:
 
Primary Antibodies
Supplier:
 
ProSci
Host Type:
 
Rabbit
Antibody Isotype:
 
Rabbit Ig
Antibody Clonality:
 
Polyclonal
Regulatory Status:
 
RUO
Target Species:
 
Human
Application:
 
Western Blot (WB)
Storage:
 
Store at 4˚C for three months and -20˚C, stable for up to one year. As with all antibodies care should be taken to avoid repeated freeze thaw cycles. Antibodies should not be exposed to prolonged high temperatures.
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Western blot analysis in Hela cell line lysates (35ug/lane).
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Western blot analysis in Hela cell line lysates (35ug/lane).

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PSI-59-225-400ul400ul£626.00
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Further Information

Additional Names:
Myotubularin-related protein 14, 313-, HCV NS5A-transactivated protein 4 splice variant A-binding protein 1, NS5ATP4ABP1, hJumpy, MTMR14, C3orf29
Application Note:
For WB starting dilution is: 1:1000
Background:
This gene encodes a myotubularin-related protein. The encoded protein is a phosphoinositide phosphatase that specifically dephosphorylates phosphatidylinositol 3,5-biphosphate and phosphatidylinositol 3-phosphate. Mutations in this gene are correlated with autosomal dominant centronuclear myopathy. Alternate splicing results in multiple transcript variants. A pseudogene of this gene is found on chromosome 18.
Background References:
  • Gibbs, E.M., et al. Autophagy 6(6):819-820(2010)
  • Rose, J.E., et al. Mol. Med. 16 (7-8), 247-253 (2010) :
  • Vergne, I., et al. EMBO J. 28(15):2244-2258(2009)
  • Tosch, V., et al. Hum. Mol. Genet. 15(21):3098-3106(2006)
Buffer:
Supplied in PBS with 0.09% (W/V) sodium azide.
Concentration:
batch dependent
Conjugate:
Unconjugated
DISCLAIMER:
Optimal dilutions/concentrations should be determined by the end user. The information provided is a guideline for product use. This product is for research use only.
Homology:
Predicted species reactivity based on immunogen sequence: Mouse
Immunogen:
This MTMR14 antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 18-45 amino acids from the N-terminal region of human MTMR14.
NCBI Gene ID #:
64419
NCBI Official Name:
Myotubularin-related protein 14
NCBI Official Symbol:
MTMR14
NCBI Organism:
Homo sapiens
Physical State:
Liquid
PREDICTED MOLECULAR WEIGHT:
72 kDa
Protein Accession #:
Q8NCE2
Protein GI Number:
118568016
Purification:
This antibody is purified through a protein A column, followed by peptide affinity purification.
Research Area:
Signal Transduction
Swissprot #:
Q8NCE2
User NOte:
Optimal dilutions for each application to be determined by the researcher.