ProSci

PCGF6 Antibody

Product Code:
 
PSI-60-168
Product Group:
 
Primary Antibodies
Supplier:
 
ProSci
Host Type:
 
Rabbit
Antibody Isotype:
 
Rabbit Ig
Antibody Clonality:
 
Polyclonal
Regulatory Status:
 
RUO
Target Species:
 
Human
Application:
 
Western Blot (WB)
Storage:
 
Store at 4˚C for three months and -20˚C, stable for up to one year. As with all antibodies care should be taken to avoid repeated freeze thaw cycles. Antibodies should not be exposed to prolonged high temperatures.
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Western blot analysis in NCI-H292,rat liver,stomach and testis cell line lysates (35ug/lane).
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Western blot analysis in NCI-H292,rat liver,stomach and testis cell line lysates (35ug/lane).

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PSI-60-168-400ul400ul£626.00
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Further Information

Additional Names:
Polycomb group RING finger protein 6, Mel18 and Bmi1-like RING finger, RING finger protein 134, PCGF6, MBLR, RNF134
Application Note:
For WB starting dilution is: 1:1000
Background:
The protein encoded by this gene contains a RING finger motif, which is most closely related to those of polycomb group (PcG) proteins RNF110/MEL-18 and BMI1. PcG proteins are known to form protein complexes and function as transcription repressors. This protein has been shown to interact with some PcG proteins and act as a transcription repressor. The activity of this protein is found to be regulated by cell cycle dependent phosphorylation. Alternatively spliced transcript variants encoding different isoforms have been identified.
Background References:
  • Lee, J.Y., et al. Cancer Res. 68(11):4201-4209(2008)
  • Zhang, J., et al. J. Biol. Chem. 283(12):7464-7469(2008)
  • Lee, M.G., et al. Cell 128(5):877-887(2007)
  • Zhong, N., et al. Biochem. Biophys. Res. Commun. 338(2):855-861(2005)
Buffer:
Supplied in PBS with 0.09% (W/V) sodium azide.
Concentration:
batch dependent
Conjugate:
Unconjugated
DISCLAIMER:
Optimal dilutions/concentrations should be determined by the end user. The information provided is a guideline for product use. This product is for research use only.
Homology:
Predicted species reactivity based on immunogen sequence: Mouse, Rat
Immunogen:
This PCGF6 antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 190-217 amino acids from the Central region of human PCGF6.
NCBI Gene ID #:
84108
NCBI Official Name:
Polycomb group RING finger protein 6
NCBI Official Symbol:
PCGF6
NCBI Organism:
Homo sapiens
Physical State:
Liquid
PREDICTED MOLECULAR WEIGHT:
39 kDa
Protein Accession #:
Q9BYE7
Protein GI Number:
116242703
Purification:
This antibody is purified through a protein A column, followed by peptide affinity purification.
Swissprot #:
Q9BYE7
User NOte:
Optimal dilutions for each application to be determined by the researcher.