ProSci

Cleavage stimulation factor 2 Antibody

Product Code:
 
PSI-60-542
Product Group:
 
Primary Antibodies
Supplier:
 
ProSci
Host Type:
 
Rabbit
Antibody Isotype:
 
Rabbit Ig
Antibody Clonality:
 
Polyclonal
Regulatory Status:
 
RUO
Target Species:
 
Human
Application:
 
Western Blot (WB)
Storage:
 
Store at 4˚C for three months and -20˚C, stable for up to one year. As with all antibodies care should be taken to avoid repeated freeze thaw cycles. Antibodies should not be exposed to prolonged high temperatures.
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Western blot analysis of anti-CSTF2 Antibody in NCI-H460 cell line lysates (35ug/lane).
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Western blot analysis of anti-CSTF2 Antibody in NCI-H460 cell line lysates (35ug/lane).

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PSI-60-542-400ul400ul£626.00
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Further Information

Additional Names:
Cleavage stimulation factor subunit 2, CF-1 64 kDa subunit, Cleavage stimulation factor 64 kDa subunit, CSTF 64 kDa subunit, CstF-64, CSTF2
Application Note:
For WB starting dilution is: 1:1000
Background:
CSTF2 is one of three (including CSTF1 and CSTF3) cleavage stimulation factors which combine to form CSTF which is involved in the polyadenylation and 3'end cleavage of pre-mRNAs. CSTF2 contains a ribonucleoprotein-type RNA binding domain. CSTF2 is upregulated during activation of B cells which results in the switch of IgM heavy chain mRNA from membrane bound form to the secreted form.
Background References:
  • Takagaki, Y., et al., Mol. Cell 2(6):761-771 (1998).
  • Martincic, K., et al., Proc. Natl. Acad. Sci. U.S.A. 95(19):11095-11100 (1998).
  • Takagaki, Y., et al., Cell 87(5):941-952 (1996).
  • Takagaki, Y., et al., Nature 372(6505):471-474 (1994).
Buffer:
Supplied in PBS with 0.09% (W/V) sodium azide.
Concentration:
batch dependent
Conjugate:
Unconjugated
DISCLAIMER:
Optimal dilutions/concentrations should be determined by the end user. The information provided is a guideline for product use. This product is for research use only.
Homology:
Predicted species reactivity based on immunogen sequence: Bovine, Mouse
Immunogen:
This Cleavage stimulation factor 2 (CSTF2) antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 31-60 amino acids from the N-terminal region of human Cleavage stimulation factor 2 (CSTF2).
NCBI Gene ID #:
1478
NCBI Official Name:
Cleavage stimulation factor subunit 2
NCBI Official Symbol:
CSTF2
NCBI Organism:
Homo sapiens
Physical State:
Liquid
PREDICTED MOLECULAR WEIGHT:
61 kDa
Protein Accession #:
P33240
Protein GI Number:
461847
Purification:
This antibody is prepared by Saturated Ammonium Sulfate (SAS) precipitation followed by dialysis
Swissprot #:
P33240
User NOte:
Optimal dilutions for each application to be determined by the researcher.