ProSci

RNH2C Antibody

Product Code:
 
PSI-63-884
Product Group:
 
Primary Antibodies
Supplier:
 
ProSci
Host Type:
 
Rabbit
Antibody Isotype:
 
Rabbit Ig
Antibody Clonality:
 
Polyclonal
Regulatory Status:
 
RUO
Target Species:
 
Human
Applications:
  • Flow Cytometry
  • Western Blot (WB)
Storage:
 
Store at 4˚C for three months and -20˚C, stable for up to one year. As with all antibodies care should be taken to avoid repeated freeze thaw cycles. Antibodies should not be exposed to prolonged high temperatures.
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Western blot analysis of RNH2C Antibody in HL-60 cell line lysates (35ug/lane).
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Flow cytometric analysis of HL-60 cells (bottom histogram) compared to a negative control cell (top histogram).FITC-conjugated goat-anti-rabbit secondary antibodies were used for the analysis.
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Western blot analysis of RNH2C Antibody in HL-60 cell line lysates (35ug/lane).
Flow cytometric analysis of HL-60 cells (bottom histogram) compared to a negative control cell (top histogram).FITC-conjugated goat-anti-rabbit secondary antibodies were used for the analysis.

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PSI-63-884-400ul400ul£626.00
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Further Information

Additional Names:
Ribonuclease H2 subunit C, RNase H2 subunit C, Aicardi-Goutieres syndrome 3 protein, AGS3, RNase H1 small subunit, Ribonuclease HI subunit C, RNASEH2C, AYP1
Application Note:
For WB starting dilution is: 1:1000

For FACS starting dilution is: 1:10~50
Background:
RNH2C encodes a ribonuclease H subunit that can cleave ribonucleotides from RNA:DNA duplexes.
Background References:
  • Chon,H., et.al., Nucleic Acids Res. 37 (1), 96-110 (2009)
  • Rice,G., et.al., Am. J. Hum. Genet. 81 (4), 713-725 (2007)
  • Crow,Y.J., et.al., Nat. Genet. 38 (8), 910-916 (2006)
Buffer:
Supplied in PBS with 0.09% (W/V) sodium azide.
Concentration:
batch dependent
Conjugate:
Unconjugated
DISCLAIMER:
Optimal dilutions/concentrations should be determined by the end user. The information provided is a guideline for product use. This product is for research use only.
Immunogen:
This RNH2C antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 80-108 amino acids from the Central region of human RNH2C.
NCBI Gene ID #:
84153
NCBI Official Name:
Ribonuclease H2 subunit C
NCBI Official Symbol:
RNASEH2C
NCBI Organism:
Homo sapiens
Physical State:
Liquid
PREDICTED MOLECULAR WEIGHT:
18 kDa
Protein Accession #:
Q8TDP1
Protein GI Number:
74730607
Purification:
This antibody is purified through a protein A column, followed by peptide affinity purification.
Swissprot #:
Q8TDP1
User NOte:
Optimal dilutions for each application to be determined by the researcher.