ProSci

ADAMTS10 Antibody

Product Code:
 
PSI-55-037
Product Group:
 
Primary Antibodies
Supplier:
 
ProSci
Host Type:
 
Rabbit
Antibody Isotype:
 
Rabbit Ig
Antibody Clonality:
 
Polyclonal
Regulatory Status:
 
RUO
Target Species:
  • Human
  • Mouse
Application:
 
Western Blot (WB)
Storage:
 
Store at 4˚C for three months and -20˚C, stable for up to one year. As with all antibodies care should be taken to avoid repeated freeze thaw cycles. Antibodies should not be exposed to prolonged high temperatures.
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Western blot analysis in mouse cerebellum tissue lysates (35ug/lane).
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Western blot analysis in mouse cerebellum tissue lysates (35ug/lane).

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PSI-55-037-400ul400ul£626.00
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Further Information

Additional Names:
A disintegrin and metalloproteinase with thrombospondin motifs 10, ADAM-TS 10, ADAM-TS10, ADAMTS-10, 3424-, ADAMTS10
Application Note:
For WB starting dilution is: 1:1000
Background:
This gene belongs to the ADAMTS (a disintegrin and metalloproteinase domain with thrombospondin type-1 motifs) family of zinc-dependent proteases. ADAMTS proteases are complex secreted enzymes containing a prometalloprotease domain of the reprolysin type attached to an ancillary domain with a highly conserved structure that includes at least one thrombospondin type 1 repeat. They have been demonstrated to have important roles in connective tissue organization, coagulation, inflammation, arthritis, angiogenesis and cell migration. The product of this gene plays a major role in growth and in skin, lens, and heart development. It is also a candidate gene for autosomal recessive Weill-Marchesani syndrome.
Background References:
  • Morales, J., et al. Am. J. Hum. Genet. 85(5):558-568(2009)
  • Ben Yahia, S., et al. J. Hum. Genet. 54(9):550-553(2009)
  • Kutz, W.E., et al. Hum. Mutat. 29(12):1425-1434(2008)
  • Gudbjartsson, D.F., et al. Nat. Genet. 40(5):609-615(2008)
Buffer:
Supplied in PBS with 0.09% (W/V) sodium azide.
Concentration:
batch dependent
Conjugate:
Unconjugated
DISCLAIMER:
Optimal dilutions/concentrations should be determined by the end user. The information provided is a guideline for product use. This product is for research use only.
Immunogen:
This ADAMTS10 antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 210-240 amino acids from the N-terminal region of human ADAMTS10.
NCBI Gene ID #:
81794
NCBI Official Name:
A disintegrin and metalloproteinase with thrombospondin motifs 10
NCBI Official Symbol:
ADAMTS10
NCBI Organism:
Homo sapiens
Physical State:
Liquid
PREDICTED MOLECULAR WEIGHT:
121 kDa
Protein Accession #:
Q9H324
Protein GI Number:
148887344
Purification:
This antibody is purified through a protein A column, followed by peptide affinity purification.
Research Area:
Cell Cycle,Signal Transduction
Swissprot #:
Q9H324
User NOte:
Optimal dilutions for each application to be determined by the researcher.