ProSci

NUBPL Antibody

Product Code:
 
PSI-59-620
Product Group:
 
Primary Antibodies
Supplier:
 
ProSci
Host Type:
 
Rabbit
Antibody Isotype:
 
Rabbit Ig
Antibody Clonality:
 
Polyclonal
Regulatory Status:
 
RUO
Target Species:
  • Human
  • Mouse
Application:
 
Western Blot (WB)
Storage:
 
Store at 4˚C for three months and -20˚C, stable for up to one year. As with all antibodies care should be taken to avoid repeated freeze thaw cycles. Antibodies should not be exposed to prolonged high temperatures.
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Western blot analysis in mouse bladder tissue lysates (35ug/lane).
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Western blot analysis in mouse bladder tissue lysates (35ug/lane).

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PSI-59-620-400ul400ul£626.00
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Further Information

Additional Names:
Iron-sulfur protein NUBPL, IND1 homolog, Nucleotide-binding protein-like, huInd1, NUBPL, C14orf127
Application Note:
For WB starting dilution is: 1:1000
Background:
Respiratory complex I (NADH:ubiquinone oxidoreductase EC 1.6.5.3) is a large mitochondrial inner membrane enzyme consisting of 45 subunits and 8 iron-sulfur (Fe/S) clusters. NUBPL, or IND1, is an Fe/ S protein that plays a critical role in the assembly of respiratory complex I, likely by transferring Fe/S into the Fe/S-containing complex I subunits (Sheftel et al., 2009 [PubMed 19752196]).
Background References:
  • Calvo, S.E., et al. Nat. Genet. 42(10):851-858(2010)
  • Sheftel, A.D., et al. Mol. Cell. Biol. 29(22):6059-6073(2009)
  • Volpi, S., et al. Mol. Psychiatry 14(11):1024-1031(2009)
  • Baranzini, S.E., et al. Hum. Mol. Genet. 18(4):767-778(2009)
Buffer:
Supplied in PBS with 0.09% (W/V) sodium azide.
Concentration:
batch dependent
Conjugate:
Unconjugated
DISCLAIMER:
Optimal dilutions/concentrations should be determined by the end user. The information provided is a guideline for product use. This product is for research use only.
Immunogen:
This NUBPL antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 40-67 amino acids from the N-terminal region of human NUBPL.
NCBI Gene ID #:
80224
NCBI Official Name:
Iron-sulfur protein NUBPL
NCBI Official Symbol:
NUBPL
NCBI Organism:
Homo sapiens
Physical State:
Liquid
PREDICTED MOLECULAR WEIGHT:
34 kDa
Protein Accession #:
Q8TB37
Protein GI Number:
116242683
Purification:
This antibody is purified through a protein A column, followed by peptide affinity purification.
Swissprot #:
Q8TB37
User NOte:
Optimal dilutions for each application to be determined by the researcher.