ProSci

FXR1 Antibody

Product Code:
 
PSI-60-914
Product Group:
 
Primary Antibodies
Supplier:
 
ProSci
Host Type:
 
Rabbit
Antibody Isotype:
 
Rabbit Ig
Antibody Clonality:
 
Polyclonal
Regulatory Status:
 
RUO
Target Species:
 
Mouse
Application:
 
Western Blot (WB)
Storage:
 
Store at 4˚C for three months and -20˚C, stable for up to one year. As with all antibodies care should be taken to avoid repeated freeze thaw cycles. Antibodies should not be exposed to prolonged high temperatures.
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Western blot analysis in mouse liver tissue lysates (35ug/lane).
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Western blot analysis in mouse liver tissue lysates (35ug/lane).

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PSI-60-914-400ul400ul£626.00
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Further Information

Additional Names:
Fragile X mental retardation syndrome-related protein 1, hFXR1p, FXR1
Application Note:
For WB starting dilution is: 1:1000
Background:
The protein encoded by this gene is an RNA binding protein that interacts with the functionally-similar proteins FMR1 and FXR2. These proteins shuttle between the nucleus and cytoplasm and associate with polyribosomes, predominantly with the 60S ribosomal subunit. Three transcript variants encoding different isoforms have been found for this gene.
Background References:
  • Coffee, R.L. Jr., et al. Dis Model Mech(7-8), 471-485 (2010) :
  • Darnell, J.C., et al. Hum. Mol. Genet. 18(17):3164-3177(2009)
  • Purcell, S.M., et al. Nature 460(7256):748-752(2009)
  • Davidovic, L., et al. J. Med. Genet. 45(10):679-685(2008)
Buffer:
Supplied in PBS with 0.09% (W/V) sodium azide.
Concentration:
batch dependent
Conjugate:
Unconjugated
DISCLAIMER:
Optimal dilutions/concentrations should be determined by the end user. The information provided is a guideline for product use. This product is for research use only.
Homology:
Predicted species reactivity based on immunogen sequence: Bovine, Hamster, Rat
Immunogen:
This FXR1 antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 37-66 amino acids from the N-terminal region of human FXR1.
NCBI Gene ID #:
8087
NCBI Official Name:
Fragile X mental retardation syndrome-related protein 1
NCBI Official Symbol:
FXR1
NCBI Organism:
Homo sapiens
Physical State:
Liquid
PREDICTED MOLECULAR WEIGHT:
70 kDa
Protein Accession #:
P51114
Protein GI Number:
189047132
Purification:
This antibody is purified through a protein A column, followed by peptide affinity purification.
Research Area:
Immunology
Swissprot #:
P51114
User NOte:
Optimal dilutions for each application to be determined by the researcher.