ProSci

Mouse Sike1 Antibody

Product Code:
 
PSI-60-937
Product Group:
 
Primary Antibodies
Supplier:
 
ProSci
Host Type:
 
Rabbit
Antibody Isotype:
 
Rabbit Ig
Antibody Clonality:
 
Polyclonal
Regulatory Status:
 
RUO
Target Species:
 
Mouse
Application:
 
Western Blot (WB)
Storage:
 
Store at 4˚C for three months and -20˚C, stable for up to one year. As with all antibodies care should be taken to avoid repeated freeze thaw cycles. Antibodies should not be exposed to prolonged high temperatures.
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Western Blot at 1:1000 dilution + mouse liver lysate Lysates/proteins at 20 ug per lane.
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Western Blot at 1:1000 dilution + mouse liver lysate Lysates/proteins at 20 ug per lane.

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PSI-60-937-400ul400ul£626.00
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Further Information

Additional Names:
Suppressor of IKBKE 1, Suppressor of IKK-epsilon, Sike1
Application Note:
For WB starting dilution is: 1:1000
Background:
Physiological suppressor of IKK-epsilon and TBK1 that plays an inhibitory role in virus-and TLR3-triggered IRF3. Inhibits TLR3-mediated activation of interferon-stimulated response elements (ISRE) and the IFN-beta promoter. May act by disrupting the interactions of IKBKE or TBK1 with TICAM1/TRIF, IRF3 and DDX58/RIG-I. Does not inhibit NF-kappa-B activation pathways (By similarity).
Background References:
  • Katayama, S., et al. Science 309(5740):1564-1566(2005)
  • Carninci, P., et al. Science 309(5740):1559-1563(2005)
Buffer:
Supplied in PBS with 0.09% (W/V) sodium azide.
Concentration:
batch dependent
Conjugate:
Unconjugated
DISCLAIMER:
Optimal dilutions/concentrations should be determined by the end user. The information provided is a guideline for product use. This product is for research use only.
Homology:
Predicted species reactivity based on immunogen sequence: Rat
Immunogen:
This Mouse Sike1 antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 36-63 amino acids from the N-terminal region of mouse Sike1.
NCBI Gene ID #:
66641
NCBI Official Name:
Suppressor of IKBKE 1
NCBI Official Symbol:
Sike1
NCBI Organism:
Mus musculus
Physical State:
Liquid
PREDICTED MOLECULAR WEIGHT:
24 kDa
Protein Accession #:
Q9CPR7
Purification:
This antibody is purified through a protein A column, followed by peptide affinity purification.
Research Area:
Immunology
Swissprot #:
Q9CPR7
User NOte:
Optimal dilutions for each application to be determined by the researcher.