ProSci

PPCDC Antibody

Product Code:
 
PSI-57-391
Product Group:
 
Primary Antibodies
Supplier:
 
ProSci
Host Type:
 
Rabbit
Antibody Isotype:
 
Rabbit Ig
Antibody Clonality:
 
Polyclonal
Regulatory Status:
 
RUO
Target Species:
 
Mouse
Application:
 
Western Blot (WB)
Storage:
 
Store at 4˚C for three months and -20˚C, stable for up to one year. As with all antibodies care should be taken to avoid repeated freeze thaw cycles. Antibodies should not be exposed to prolonged high temperatures.
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Western blot analysis in mouse kidney tissue lysates (35ug/lane).
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Western blot analysis in mouse kidney tissue lysates (35ug/lane).

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PSI-57-391-400ul400ul£626.00
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Further Information

Additional Names:
Phosphopantothenoylcysteine decarboxylase, PPC-DC, CoaC, PPCDC, COAC
Application Note:
For WB starting dilution is: 1:1000
Background:
Biosynthesis of coenzyme A (CoA) from pantothenic acid (vitamin B5) is an essential universal pathway in prokaryotes and eukaryotes. PPCDC (EC 4.1.1.36), one of the last enzymes in this pathway, converts phosphopantothenoylcysteine to 4-prime-phosphopantetheine (Daugherty et al., 2002 [PubMed 11923312]).
Background References:
  • Strauss, E., et al. Biochemistry 43(49):15520-15533(2004)
  • Manoj, N., et al. Acta Crystallogr.Biol. Crystallogr. 59 (PT 10), 1762-1766 (2003) :
  • Daugherty, M., et al. J. Biol. Chem. 277(24):21431-21439(2002)
Buffer:
Supplied in PBS with 0.09% (W/V) sodium azide.
Concentration:
batch dependent
Conjugate:
Unconjugated
DISCLAIMER:
Optimal dilutions/concentrations should be determined by the end user. The information provided is a guideline for product use. This product is for research use only.
Immunogen:
This PPCDC antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 37-66 amino acids from the N-terminal region of human PPCDC.
NCBI Gene ID #:
60490
NCBI Official Name:
Phosphopantothenoylcysteine decarboxylase
NCBI Official Symbol:
PPCDC
NCBI Organism:
Homo sapiens
Physical State:
Liquid
PREDICTED MOLECULAR WEIGHT:
22 kDa
Protein Accession #:
Q96CD2
Protein GI Number:
296434457
Purification:
This antibody is purified through a protein A column, followed by peptide affinity purification.
Research Area:
Obesity,Signal Transduction
Swissprot #:
Q96CD2
User NOte:
Optimal dilutions for each application to be determined by the researcher.