ProSci

MBL Recombinant Protein

Product Code:
 
PSI-96-922
Product Group:
 
Recombinant Proteins
Supplier:
 
ProSci
Regulatory Status:
 
RUO
Target Species:
 
Human
Application:
 
Western Blot (WB)
Storage:
 
Lyophilized Protein should be stored at -20˚C or lower for long term storage. Upon reconstitution, working aliquots should be stored at -20˚C or -70˚C. Avoid repeated freeze-thaw cycles.
 

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PSI-96-922-0.1mg0.1mg£597.00
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Further Information

Additional Names:
MBL,MBL2,MBP1,MBP-C,Collectin-1,COLEC1,HSMBPC,MBL2D,MBPD
Application Note:
This recombinant protein can be used for WB. For research use only.
Background:
Mannose-binding lectin (MBL) is also known as mannose-binding protein, mannan-binding protein (MBP), Mannose-binding protein C, Collectin-1 (COLEC1), MBL2, which belongs to the class of collectins in the C-type lectin superfamily. MBL contains one C-type lectin domain and one collagen-like domain. MBL has an oligomeric structure (400-700 kDa), built of subunits that contain three presumably identical peptide chains of about 30 kDa each. MBL is calcium-dependent lectin involved in innate immune defense. MBL binds mannose, fucose and N-acetylglucosamine on different microorganisms and activates the lectin complement pathway. MBL binds to late apoptotic cells. MBL may bind DNA.
Background References:
  • Nauta A.J., et al., 2003, Eur. J. Immunol. 33:2853-2863.
  • Hirano M., et al., 2005, J. Immunol. 175:3177-3185.
Buffer:
PBS, pH7.4
Fusion Tag:
His Tag
NCBI Gene ID #:
4153
NCBI Official Name:
Mannose-binding lectin (protein C) 2, soluble (opsonic defect)
NCBI Official Symbol:
MBL
NCBI Organism:
Homo sapiens
Physical State:
Lyophilized
Predicted Molecular Weight:
24.8 kDa
Protein Accession #:
AAH96179
Purity:
>95% as determined by SDS-PAGE.

Endotoxin level is less than 1.0 EU per ug by the LAL method.
Recombinant Protein Sequence:
Thr32-Gly402
Source:
HEK293 cells
Swissprot #:
P11226

Documents