Further Information
Alternate Names/Synonyms:
Rifamycin AF/EPTAPI; 3-[[(4-Heptyl-1-piperazinyl)imino]methyl]-rifamycin
Red powder.
41971-22-6
32160000
liquid
Keep cool and dry.Protect from light.Protect from light when in solution.
InChI=1S/C49H70N4O12/c1-11-12-13-14-15-20-52-21-23-53(24-22-52)50-26-34-39-44(59)37-36(43(34)58)38-46(32(7)42(37)57)65-49(9,47(38)60)63-25-19-35(62-10)29(4)45(64-33(8)54)31(6)41(56)30(5)40(55)27(2)17-16-18-28(3)48(61)51-39/h16-19,25-27,29-31,35,40-41,45,55-59H,11-15,20-24H2,1-10H3,(H,51,61)/b17-16+,25-19+,28-18-,50-26+/t27-,29+,30+,31+,35?,40-,41+,45+,49-/m0/s1
XLFXMDIMYQHPNA-HJYHSKLVSA-N
Chemical. CAS: 41971-22-6. Formula: C49H70N4O12. MW: 907.1. Semisynthetic. Ansamycin antibiotic. Selective inhibitor of bacterial DNA-dependent RNA polymerase (RNAP). Effective against mycobacteria, and are therefore used in research of tuberculosis, leprosy and mycobacterium avium complex (MAC) infections.
C49H70N4O12
907.1
Vial
Ansamycin antibiotic. Selective inhibitor of bacterial DNA-dependent RNA polymerase (RNAP). Effective against mycobacteria and therefore used in research of tuberculosis, leprosy and Mycobacterium avium complex (MAC) infections.
>98% (HPLC)
OC1=C(NC(/C(C)=CC=C[C@H](C)[C@H](O)[C@@H](C)[C@H]([C@@H](C)[C@@H]([C@H](C)[C@H](/C=C/O2)OC)OC(C)=O)O)=O)C(/C=N/N3CCN(CCCCCCC)CC3)=C(O)C4=C5C(O[C@@]2(C)C5=O)=C(C)C(O)=C41
Soluble in DMSO, aqueous acetonitrile or ethanol.
Semisynthetic.
Non-hazardous
Natural Products/Extracts
12352200
Stable for at least 2 years after receipt when stored at -20°C.