Further Information
Alternate Names/Synonyms:
NCI 144-111; 4-[(Aminoiminomethyl)azo]-4-deoxy-rifamycin
Red powder.
38128-51-7
32160000
liquid
Keep cool and dry.Protect from light.Protect from light when in solution.
InChI=1S/C38H49N5O11/c1-16-11-10-12-17(2)36(50)41-24-15-23(42-43-37(39)40)26-27(32(24)48)31(47)21(6)34-28(26)35(49)38(8,54-34)52-14-13-25(51-9)18(3)33(53-22(7)44)20(5)30(46)19(4)29(16)45/h10-16,18-20,25,29-30,33,45-47H,1-9H3,(H,41,50)(H4,39,40,43)/b11-10+,14-13+,17-12-,42-23+/t16-,18+,19+,20+,25?,29-,30+,33+,38-/m0/s1
LGCZXXFOLXAQNH-AYTZBZETSA-N
Chemical. CAS: 38128-51-7. Formula: C38H49N5O11. MW: 751.8. Semisynthetic. Ansamycin antibiotic. Selective inhibitor of bacterial DNA-dependent RNA polymerase (RNAP). Effective against mycobacteria, and are therefore used in research of tuberculosis, leprosy and mycobacterium avium complex (MAC) infections.
C38H49N5O11
751.8
Vial
Ansamycin antibiotic. Selective inhibitor of bacterial DNA-dependent RNA polymerase (RNAP). Effective against mycobacteria and therefore used in research of tuberculosis, leprosy and Mycobacterium avium complex (MAC) infections.
>98% (HPLC)
O=C1C(N2)=C/C(C3=C1C(O)=C(C)C(O[C@]4(C)O/C=C/[C@H](OC)[C@@H](C)[C@@H](OC(C)=O)[C@H](C)[C@H](O)[C@H](C)[C@@H](O)[C@@H](C)/C=C/C=C(C)C2=O)=C3C4=O)=NNC(N)=N
Soluble in DMSO, aqueous acetonitrile or ethanol.
Semisynthetic.
Non-hazardous
Natural Products/Extracts
12352200
Stable for at least 2 years after receipt when stored at -20°C.