NSJ Bioreagents

Beta Arrestin 1 Antibody

Product Code:
 
NSJ-R31275
Product Group:
 
Primary Antibodies
Supplier:
 
NSJ Bioreagents
Host Type:
 
Rabbit
Antibody Isotype:
 
Rabbit IgG
Antibody Clonality:
 
Polyclonal
Regulatory Status:
 
RUO
Target Species:
  • Human
  • Mouse
  • Rat
Applications:
  • Immunohistochemistry- Paraffin Embedded (IHC-P)
  • Western Blot (WB)
Storage:
 
After reconstitution, the beta Arrestin 1 antibody can be stored for up to one month at 40. For long-term, aliquot and store at -200. Avoid repeated freezing and thawing.
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Western blot testing of beta Arrestin 1 antibody and Lane 1: rat lung; 2: rat skeletal muscle; 3: human SW620 cell lysate~
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IHC-P: beta Arrestin 1 antibody testing of human breast cancer tissue
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Western blot testing of beta Arrestin 1 antibody and Lane 1: rat lung; 2: rat skeletal muscle; 3: human SW620 cell lysate~
IHC-P: beta Arrestin 1 antibody testing of human breast cancer tissue

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NSJ-R31275-100ug100 ug£535.00
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Further Information

Application Details :
Western blot: 0.5-1ug/ml,Immunohistochemistry (FFPE): 0.5-1ug/ml
Application Note:
The stated application concentrations are suggested starting amounts. Titration of the beta Arrestin 1 antibody may be required due to differences in protocols and secondary/substrate sensitivity.
Description:
Beta Arrestin 1 is a protein which in humans is encoded by the ARRB1 gene. Members of arrestin/beta-arrestin protein family are though to participate in agonist-mediated desensitization of G-protein-coupled receptors and cause specific dampening of cellular responses to stimuli such as hormones, neurotransmitters, or sensory signals. By fluorescence in situ hybridization,this gene is mapped to 11q13.4. Beta Arrestin 1 is a cytosolic protein and acts as a cofactor in the beta-adrenergic receptor kinase (BARK) mediated desensitization of beta-adrenergic receptors. Besides the central nervous system, it is expressed at high levels in peripheral blood leukocytes, and thus the BARK/beta-arrestin system is believed to play a major role in regulating receptor-mediated immune functions.
Format :
Antigen affinity purified
Formulation :
0.5mg/ml if reconstituted with 0.2ml sterile DI water
Immunogen:
An amino acid sequence from the N-terminus of human ARRB1 (ANVQSFPPAPEDKKPLTRLQER) was used as the immunogen for this beta Arrestin 1 antibody (100% homologous in human, mouse and rat).
Limitation:
This beta Arrestin 1 antibody is available for research use only.
Purity:
Antigen affinity
Species Reactivity :
Human, Mouse, Rat
Uniprot #:
P49407