NSJ Bioreagents

Fas Antibody

Product Code:
 
NSJ-R31665
Product Group:
 
Primary Antibodies
Supplier:
 
NSJ Bioreagents
Host Type:
 
Rabbit
Antibody Isotype:
 
Rabbit IgG
Antibody Clonality:
 
Polyclonal
Regulatory Status:
 
RUO
Target Species:
 
Human
Applications:
  • Immunohistochemistry- Paraffin Embedded (IHC-P)
  • Western Blot (WB)
Storage:
 
After reconstitution, the Fas antibody can be stored for up to one month at 40. For long-term, aliquot and store at -200. Avoid repeated freezing and thawing.
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Western blot testing of Fas antibody and Lane 1: HeLa; 2: Jurkat; 3: A549; 4: SMMC-7721; 5: K562 lysate
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Western blot testing of Fas antibody and recombinant human protein (0.5ng)
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IHC-P: Fas antibody testing of human lung cancer tissue
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Western blot testing of Fas antibody and Lane 1: HeLa; 2: Jurkat; 3: A549; 4: SMMC-7721; 5: K562 lysate
Western blot testing of Fas antibody and recombinant human protein (0.5ng)
IHC-P: Fas antibody testing of human lung cancer tissue

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NSJ-R31665-100ug100 ug£535.00
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Further Information

Application Details :
Western blot: 0.5-1ug/ml,Immunohistochemistry (FFPE): 0.5-1ug/ml
Application Note:
The stated application concentrations are suggested starting points. Titration of the Fas antibody may be required due to differences in protocols and secondary/substrate sensitivity.
Description:
Fas (also known as surface antigen APO1 or CD95) is a member of the tumour-necrosis receptor factor family of death receptors. It acts as an inducer of both neurite growth in vitro and accelerated recovery after nerve injury in vivo. FAS antigen is expressed and functional on papillary thyroid cancer cells and this may have potential therapeutic significance. The antigen shows structural homology with a number of cell surface receptors, including tumor necrosis factor(TNF) receptors and the low-affinity nerve growth factor receptor(NGFR) and it is mapped to 10q24.1. The FAS/FASL system plays a key role in regulating apoptotic cell death and corruption of this signalling pathway has been shown to participate in immune escape and tumorigenesis.
Format :
Antigen affinity purified
Formulation :
0.5mg/ml if reconstituted with 0.2ml sterile DI water
Gene ID #:
355
Immunogen:
Human partial recombinant protein (AA 26-173) was used as the immunogen for this Fas antibody.
Limitation:
This Fas antibody is available for research use only.
Purity:
Antigen affinity
Species Reactivity :
Human