NSJ Bioreagents

PGE Receptor Antibody, EP1 subtype

Product Code:
 
NSJ-R30660
Product Group:
 
Primary Antibodies
Supplier:
 
NSJ Bioreagents
Host Type:
 
Rabbit
Antibody Isotype:
 
Rabbit IgG
Antibody Clonality:
 
Polyclonal
Regulatory Status:
 
RUO
Target Species:
 
Human
Application:
 
Western Blot (WB)
Storage:
 
After reconstitution, the PGE Receptor antibody can be stored for up to one month at 40. For long-term, aliquot and store at -200. Avoid repeated freezing and thawing.
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Western blot testing of PGE Receptor antibody and Lane 1: HeLa; 2: A549; 3: MCF-7; 4: MM231; 5: MM453 cell lysate
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Western blot testing of PGE Receptor antibody and Lane 1: HeLa; 2: A549; 3: MCF-7; 4: MM231; 5: MM453 cell lysate

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NSJ-R30660-100ug100 ug£535.00
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Further Information

Application Details :
Western blot: 0.5-1ug/ml
Application Note:
The stated application concentrations are suggested starting amounts. Titration of the PGE Receptor antibody may be required due to differences in protocols and secondary/substrate sensitivity.
Description:
Prostaglandin E Receptor 1 is a 402 amino acid protein with a predicted molecular mass of 44KD and has the seven transmembrane-spanning domains common to all G protein-coupled receptors. The PTGER1 gene is mapped to chromosome 19p13.1. The protein encoded by this gene is a member of the G protein-coupled receptor family. This protein is one of four receptors identified for prostaglandin E (PGE). Through a phosphatidylinositol-calcium second messenger system, Gq proteins mediate this receptor's activity. Knockout studies in mice suggested a role of this receptor in mediating algesia and in regulation of blood pressure. Studies in mice also suggested that this gene may mediate adrenocorticotropic hormone response to bacterial endotoxin.
Format :
Antigen affinity purified
Formulation :
0.5mg/ml if reconstituted with 0.2ml sterile DI water
Immunogen:
An amino acid sequence from the C-terminus of human PGE Receptor EP1 subtype (AWEASSLRSSRHSGLSHF) was used as the immunogen for this PGE Receptor antibody.
Limitation:
This PGE Receptor antibody is available for research use only.
Purity:
Antigen affinity
Species Reactivity :
Human
Uniprot #:
P34995