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The Single Doman Antibody (sdAb) from camelids, also known as VHH antibodies, provides cutting-edge technology for antibody research. The sdAb lacks light chains and is smaller and more stable than conventional antibodies yet possesses fully functional antigen-binding capability. Due to its size (a mere 15 kDa), a single domain antibody is adept at reaching otherwise inaccessible epitopes. • Smallest functional antibody unit at ~15 kDa • Unique binding capacity to conformational epitopes and active sites • Unique physical properties can lead to increased stability under extreme temerature and pH, as well as increased solubility • Recombinantly produced for lot-to-lot reporducibility • Adaptable through antibody engineering • Products for Immune Checkpoints and SARS_Cov_2 targets.
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Antibodies
ProSci
ProSci offers an extensive catalog of influenza research reagents for researchers worldwide. Reagents include influenza A detection sets, influenza matched pair antibodies (for influenza A and B), and more antibodies and recombinant proteins for the different strains of influenza viral antigen. • Extensive catalog of antibodies against diverse Influenza A viruses (IAVs) such as H1, H3, H5, H7, N1, N2, N9, etc. • Antibodies produced in mice, rabbits, and goats against different peptides or recombinant protein with potential for matched pairs • Diverse applications with corresponding validation data • Affordable custom services available, including camelid single domain recombinant services
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Virology
ProSci
ProSci offers antibodies specific for point mutations in the Spike protein unique to Variants of Concern, including Omicron and Delta. • Target specific point mutations in the Spike protein • Bridge the knowledge gap between RNA analysis and protein expression • Build your own toolbox to investigate SARS-CoV-2 gene expression • Study circulating variants at protein level • Determine viral protein distribution in tissues
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COVID-19
ProSci
3D Brain Models, 3D Liver Models, 3D Bone Models, 3D Spheroids Using Primary Cells, Collagen-based 3D Cell Culture Kits
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Cell Culture
Sciencell
Elabscience Biotechnology present their guide to designing multi-colour antibody panels for flow cytometry. The guide includes: Panel Design Principles, Steps of Multi-Color Panel Design, Case Studies of Multi-Color Panel Design, and highlights the Data Analysis Services offered by Elabscience. Also check out our website for a list of conjugated antibodies suitable for flow cytometry.
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Flow Cytometry
Elabscience
BioConcept Special Media Guide: Hybridoma Express Media, Insect Cell Culture Media, SF-4 Baculo Express Medium, BSK-H Medium for the cultivation of Borrelia spec., Stem Cell Media
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Cell Culture
BioConcept
SF-4 Baculo Express Serum Free Insect Medium from BioConcept: Extensive development and further investigation on the nutritional needs of insect cells, based on the excellent performance of SF-1, resulted in our improved “ready to use” SF-4 Baculo Express medium. SF-4 Baculo Express medium is a proprietary serum free formulation which has successfully been used to grow various Spodoptera frugiperda (SF9, SF21), BTI-TN5B1-4 (High FiveTM) and Drosophila melanogaster (D.Mel-2) cells. With SF-4 Baculo Express media all cell types can be cultivated: monolayer-, spinner- or shaking cultures, adherent cells and suspension cells. The medium contains all additives necessary for the cultivation of insect cells in the optimal concentration: steroids, amino acids, organic acids, glutamine and glucose. The medium is designed for efficient infection and expression with the Baculovirus system.
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Cell Culture
BioConcept
MAM-PF® from BioConcept: CHO PRODUCTION MEDIA. Benefits at a glance: - ACF (Animal Component Free) - Chemically defined - High cell densities - Pharmaceutical application - High product yield
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Cell Culture
BioConcept
AMIMED® is the brand name of BioConcept‘s cell and tissue culture product line. Manufactured in Switzerland, BioConcept offer you a broad range of special and standard (classical) media and the opportunity to create the optimum menu for your cells. The production plant is not only excellently suited for the production of cell culture media; it can also be used to manufacture sterile QC liquids and microbial broths and agars. BioConcept's product line includes: Special customer-designed media, Individual solutions for your cell culture problem, Complete cell systems applications, Standard media, Serum free and animal component (ACF) free media, Liquid and powder media, Animal sera, Buffers and balanced salt solutions, Supplements and auxiliary reagents
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Cell Culture
BioConcept
BioConcept have been producing within a certified quality management system since 1995 and their new cell culture and sterile liquid production plant has vastly improved their already high standards. BioConcept Ltd.’s expansion into the tissue culture market in 1992 allowed them to meet the needs of the sophisticated and evolving pharmaceutical and bio-pharmaceutical markets: Classical Media, Special Media, Salt Solutions, Buffers, Water, Reagents, Supplements, Sera, Technical Information
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Cell Culture
BioConcept
Serum is a highly variable non-standardized product requiring extensive testing to find the batch compatible with your cell types. The composition of serum-free medium on the other hand is well defined and ensures lot-to-lot consistency. Bioconcept's BIT 9500 Serum Substitute replaces serum for the culture of stem cells and was developed for use in serum-free culture conditions with defined composition. BIT 9500 contains Bovine serum albumin (BSA), Insulin and Transferrin (BIT) in Iscove’s IMDM. For BSA we use tested batches of EDQM certified ProbuminTM BSA.
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Cell Culture
BioConcept
Human hepatocytes have become the gold standard for evaluating hepatic metabolism and toxicity of drugs and other xenobiotics in vitro. Moreover, they are becoming utilized more extensively for many kinds of biomedical research, including a variety of biological, pharmacological and toxicological studies. For this reason, hepatocyte acquisition is now a critical step for research activities. The limited availability of human hepatocytes makes cryopreservation a good option to provide researchers with a sufficient amount of viable liver cells.
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Liver
BeCytes Biotechnologies
Hepatic non-parenchymal cells (NPCs) represent about 30% of the liver and are specialized cells which interact with hepatocytes, presenting present organotypic hepatocyte-NPC interactions via direct contact or paracrine signaling, and forming a functional hepatic unit.
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Liver
BeCytes Biotechnologies
Hepatic stellate cells (HSC) are pericytes located in the space of Disse. These cells are the major cell type involved in liver fibrosis in response to liver injury. HSC play a key role in liver homeostasis, maintenance and regeneration including retinol metabolism storage, and release.
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Liver
BeCytes Biotechnologies
Shorten the development time for new treatment technologies and cures to reach patients by ordering with StemExpress. We are dedicated to meeting the needs of researchers by providing a reliable and timely source of human-derived blood products. THE PURITY, VIABILITY, AND QUALITY YOU NEED FOR EVERY PRODUCT. Bone Marrow, Mobilized Peripheral Blood, Peripheral Blood, Cord Blood, Primary Cells, Cultured Cells, Leukopaks®, Adult Tissues, Maternal Blood
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Biological Samples
StemExpress
The Zen-Bio ORAC and ABTS Antioxidant Assay Kits can be used to determine the total antioxidant capacity of biological fluids, cells, and tissue. It can also be used to assay the antioxidant activity of naturally occurring or synthetic compounds for use as dietary supplements, topical protection, and therapeutics.
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Kits
ZenBio
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Neuroscience
AdipoGen Life Sciences
IL-33 is a nuclear-associated cytokine that is normally released by damaged or necrotic cells acting as an “alarmin”, an immediate indicator of tissue stress. IL-33 is a potent inducer of type 2 immune responses in the context of parasite infections and allergic asthma. New studies have also extended the biology of IL-33 with other functions: i) inducing brown and beige adipocyte thermogenesis and promoting insulin secretion by pancreatic islets; ii) facilitating Treg proliferation to suppress autoimmunity and to potentiate neurological recovery; and iii) exerting multiple roles in the brain.
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Immunology
AdipoGen Life Sciences
Documents
ELISA
Cloud-Clone Corp.
AdipoGen Life Sciences (AdipoGen) is a research company developing proteins, biochemicals, antibodies and ELISA Kits. To promote the advancement of non-animal alternative approaches (3Rs), AdipoGen implemented the antibody phage display technology in-house to develop monoclonal antibodies without the use of animals. Using this technology, AdipoGen was a forerunner in releasing the first recombinant monoclonal antibody for research on the market in 2010: anti-APRIL (mouse), mAb (rec.) (blocking) (Apry-1-1). Since then, our portfolio of fully validated recombinant antibodies made with the phage display technology continues to grow, with a focus on functional antibodies that can block or activate their respective target.
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Antibodies
AdipoGen Life Sciences
From raw materials to produce rapid tests, to custom peptide synthesis, ElabScience is committed to providing scientists with the tools to perform SARS-CoV-2 research.
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COVID-19
Elabscience
The kit is a sandwich enzyme immunoassay for in vitro quantitative measurement of MUC1 in mouse tissue homogenates, cell lysates, cell culture supernates and other biological fluids
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ELISA
Cloud-Clone Corp.
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Proteins
Cloud-Clone Corp.
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ELISA
Cloud-Clone Corp.
iCell® Cardiomyocytes2 are cardiac myocytes derived from human induced pluripotent stem cells (iPSC). These cardiomyocytes, which are an extension of the well-characterized iCell product line, have been optimized for faster recovery from cryopreservation and can be used in a myriad of functional applications. The recent article by Block et al. in Scientific Reports indicates that iCell Cardiomyocytes2 have enhanced functional and structural benefits following culture on CELLvo™ Matrix Plus plates for seven days. This application protocol was produced by FUJUFILM Cellular Dynamics, Inc. and details the steps for plating iCell Cardiomyocytes2 on the CELLvo™ Matrix Plus plates
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Cell Culture
StemBioSys