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Histone acetylation and histone deacetylation involve the addition or removal of an acetyl group on lysine residues in the N-terminal tail and on the surface of the nucelosome core of histone proteins. Acetylated and deacetylated histones are considered epigenetic tags within chromatin by relaxing (euchromatin) or tightening (heterochromatin) chromatin structure, subsequently increasing or decreasing gene transcription levels.

Caltag Medsystems provides a wide range of acetylation quantification, inhibitor screening & isolation kits, highly validated antibodies, recombinant proteins, inhibitors and more for the study of histone acetylation.