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Viral applications: Enhancing AAV transduction
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Transduction
Oz Biosciences
In Vitro Transfection, In Vivo Gene Delivery. Primary Neurons and Neural Cells Microglial Cells Brain: In vivo Nucleic Acid Delivery
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Neuroscience
Oz Biosciences
INTEGRATED MRNA SERVICE FROM GENE SYNTHESIS TO IVT MRNA PRODUCTION
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Service
Oz Biosciences
Magnetic Nanoparticle Technology - Virus Capture, Concentration & Conservation
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Transduction
Oz Biosciences
Enhancing lentiviral transduction
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Transduction
Oz Biosciences
RESEARCH GRADE ADJUVANTS FOR PROTEIN BASED VACCINES AND mRNA/DNA VACCINES
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Vaccine Adjuvants
Oz Biosciences
Lentiviral production
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Transfection
Oz Biosciences
THE MOST PROMISING NON-VIRAL DRUG DELIVERY NANOSYSTEMS
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Nanoparticles
Oz Biosciences
Adult Stem Cells - Embryonic Stem Cells, Induced Pluripotent Stem Cells (iPS)
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Stem Cells
Oz Biosciences
High Throughput Screening In vivo Transfection 3D Transfection
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Transfection
Oz Biosciences
Large-Scale Protein Production
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Transfection
Oz Biosciences
Magnetic-Assisted Transfection Enhance Transfection Efficiency Gene Expression - Gene Silencing, CRISPR/Cas9 Genome Editing, In vivo & Ex vivo Transfection
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Transfection
Oz Biosciences
Neuroscience Applications: Hippocampal, Cortical, Motor Neurons, Dopaminergic, Glioblastoma, Neuroblastoma, DRG, Neural Stem cells, Oligodendrocytes... Successfully transfected
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Transfection
Oz Biosciences
Vaccine, Gene Reporter, Genome Editing & Gene Replacement mRNAs
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RNA
Oz Biosciences
HIGH-QUALITY VIRAL ENHANCER
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Transduction
Oz Biosciences
Protein Quantification Assays Enzyme Detection - Reporter Gene Assays Viability / Apoptosis / Stress Assays
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Cell Based Assays
Oz Biosciences
Abnova provides a range of Tumour-Associated Antigens of CAR T Cell Therapy.
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Cancer
Abnova Corporation
Abnova provides a range of antibodies for research into TNF-TRAF Signalling.
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Immunology
Abnova Corporation
Abnova provides a range of reagents for research into the role of Tumour Necrosis Factor in Amyotrophic Lateral Sclerosis.
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Neuroscience
Abnova Corporation
T-cell-dependent antibody response (TDAR) to an antigen is a gold standard in vivo assessment of immunotoxicity at the preclinical stage of drug discovery. Abnova offers a wide variety of ELISA kits for biomarkers used in TDAR assays.
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ELISA
Abnova Corporation
Approximately there are 10% of patients with NSCLC in the US and 35% in Asia harboring EGFR mutations. EGFR mutations occur within exons 18–21 encoding a portion of the EGFR kinase domain. These mutations affect the kinase activity of EGFR, leading to downstream pro-survival signaling pathways. EGFR mutations confer sensitivity of EGFR TKI and as well as are involved in mechanisms of acquired resistance to EGFR TKI therapy. Resistance can occur through secondary resistance mutations (such as T790M) occurring in the ATP-binding domain.
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Cancer
Abnova Corporation
Also known as NS7; B-raf; BRAF1; RAFB1; B-RAF1, is a member of the RAF family of serine/threonine protein kinases activating the MAP kinase/ERK-signaling pathway and normally involved in regulating cell differentiation, proliferation, growth, and apoptosis. BRAF V600E mutation drives tumor growth by hyperactivating the extracellular signal regulated kinase (ERK) signaling pathway in the absence of any extracellular stimuli.
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Cancer
Abnova Corporation
Exhausted T cells have been identified to accumulate in tumour microenvironment (TME) and fail to eliminate cancer cells. The exhaustion is characterised by the expression of multiple inhibitory molecules, including PD-1 and CTLA4. PD-1/PD-L1 signaling antagonises TCR signaling and induces the transcription of exhaustion-related genes. Both PD-1/PD-L1 and CTLA4 signaling inhibit the pathways that promote cell cycle arrest in T cells. The inhibition of PI3K/Akt/mTOR pathway mediated by PD-1/PD-L1 or CTLA4 also leads to decreases in glycolysis and amino acid metabolism and suppresses mitochondrial biogenesis. These exhaustion-related changes result in dysfunctional T cells, which are obstacles to effective tumour immunotherapy.
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Cancer
Abnova Corporation
Neutralising antibodies are able to block the interaction between viruses and host cells, which can potentially stop the infection. Abnova has developed a group of SARS-CoV-2 S monoclonal antibodies, which are neutralising mouse monoclonal antibodies targeting recombinant SARS-CoV-2 spike protein.
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COVID-19
Abnova Corporation
Abnova provides a range of antibodies specific for renal cell carcinomas.
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Cancer
Abnova Corporation