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Despite overwhelming evidence demonstrating the important role of the extracellular matrix in regulating cell behavior, traditional cell culture strategies do little to recreate a natural microenvironment. Presently, standard culture conditions inevitably lead to phenotypic drift, spontaneous differentiation, replicative senescence, and aberrant phenotypes that are unlike those found in the body. This may lead to experimental artifact in basic research or suboptimal clinical outcomes in translational research. To address this challenge, we focused our efforts on developing in vitro culture substrates that closely mimic natural microenvironments. Here we describe the development of scale-able, tissue-specific, cell-derived extracellular matrices for cell culture, and their applications in basic and translation research.
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Cell Culture
StemBioSys
The innate immune system plays an essential role in the host's first line of defense against microbial invasion and involves the recognition of pathogen-associated molecular patterns (PAMPs) or endogenous danger signals through the sensing of danger-associated molecular patterns (DAMPs) by pattern recognition receptors (PRRs).
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Immunology
AdipoGen Life Sciences
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Immunology
AdipoGen Life Sciences
MultimericCD40L – A Potent B Cell Expansion Tool, and much more reagents
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Immunology
AdipoGen Life Sciences
Glycobiology is an integrative science, crossing the fields of chemistry, biology, medicine and material science. In the broadest sense, glycobiology is the study of the structure, biosynthesis and biology of glycans (oligosaccharides, carbohydrates), which are present in every living organism
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Molecular Biology
AdipoGen Life Sciences
Erythroferrone (also called Myonectin, CTRP15, Fam132B or ERFE) is a hormone produced by erythroblasts in the bone marrow in response to erythropoietin controlling iron storage release or is a myokine abundantly expressed in skeletal muscle tissue, upregulated by voluntary exercise.
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Cardiovascular
AdipoGen Life Sciences
MHC Class I and Class II Allele List
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Tetramers
MBL
Immunology Products, Specificity & Sensitivity, Reproducibility & Reliability. Fast Track Your Research with 30 years of experience and expertise, high quality is the hallmark of Diaclone, firmly establishing us as a centre of excellence in Monoclonal Antibody research and Immunoassay Kit development.
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Immunoassay
Diaclone
Immune Checkpoint Proteins, Interleukins & Cytokines
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Immunology
Chimerigen
Regulation and activation of T lymphocytes depend on signaling by the T cell receptor (TCR) and also by cosignaling receptors that deliver negative or positive signals
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Immunology
AdipoGen Life Sciences
Insulin is a protein hormone secreted by islet beta cells in the pancreas. Insulin is involved in regulating glucose metabolism and controlling blood sugar balance. It can be used to treat diabetes mellitus.
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ELISA
Cloud-Clone Corp.
Caspase-3 (CASP3), also known as cysteine protease 3, is a protease that can specifically cut poly-ADP ribose polymerase (PARP1) and acetyl-DEVD-7-amino-4-methyl coumarin (Ac-DEVD-AMC)...
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ELISA
Cloud-Clone Corp.
TGFb1 belongs to the TGF-βfamily, the highest proportion (>90%), and the most active multi-functional cell activity regulator
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ELISA
Cloud-Clone Corp.
Testosterone is a steroid hormone secreted by male testes or female ovaries. The adrenal gland also secretes a small amount of testosterone, which has two effects on humans and other vertebrates: directly or in the form of serum dihyd- rotestosterone (DHT) to activate androgen receptors; and converted to estradiol to activate some estrogen receptors
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ELISA
Cloud-Clone Corp.
Osteocalcin (OC), also known as R-hydroxy glutamic acid protein (GLa protein), is a protein consisting of 49 amino acids...
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ELISA
Cloud-Clone Corp.
Mucin is secreted by a special epithelial cell, the goblet cell, and covers a wide range of epithelial cell surfaces such as the trachea, bronchi etc...
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ELISA
Cloud-Clone Corp.
Cytomark have developed a specific TransFix Vacuum Blood Collection Tube for stabilising circulating tumour cells (CTCs) in blood samples.
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Flow Cytometry
Cytomark
TransFix is a stabilisation reagent that preserves cellular antigens and prevents cellular degradation in a variety of specimen types for flow cytometric analysis.
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Flow Cytometry
Cytomark
TransFix stabilisation of exosomes (extracellular vesicles) and exosomal microRNA
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Flow Cytometry
Cytomark
Preserve cellular antigens and prevent cellular degradation for up to 14 days with TransFix /EDTA Vacuum Blood Collection Tubes (IVD)
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Flow Cytometry
Cytomark
EnoGene Biotech Co. Ltd, is a biological high-tech corporation that specialises in developing and production of antibody related products
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Antibodies
Enogene Biotech
The cell adhesion molecules (CAMs) family includes more than 50 proteins with four main groups: immunoglobulin (Ig)-like CAMs, cadherins, selectins, and integrins.
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Cancer
Diaclone
New Products including Antibodies, ELISA Kits and product size alterations
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Immunoassay
Diaclone
ReZolve Scientific provides unique imaging solutions which will reduce your preparation and extend your imaging time. The proprietary ReZolveâ„¢ and Ira-Zolveâ„¢ dyes are derived from low-spin transition metal complexes.
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Probes
AdipoGen Life Sciences
Collagen has a unique triple helical structure that is unfolded in tissues during diseases, development, mechanical injury, and decellularization.
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Proteins
3Helix