ZEB2 Antibody (SIP1)
| Code | Size | Price |
|---|
| NSJ-R31649-100ug | 100 ug | £535.00 |
Quantity:
Prices exclude any Taxes / VAT
Overview
Host Type: Rabbit
Antibody Isotype: Rabbit IgG
Antibody Clonality: Polyclonal
Regulatory Status: RUO
Target Species: Human
Application: Western Blot (WB)
Storage:
After reconstitution, the ZEB2 antibody can be stored for up to one month at 40. For long-term, aliquot and store at -200. Avoid repeated freezing and thawing.
Documents
Further Information
Application Details :
Western blot: 0.5-1ug/ml
Application Note:
The stated application concentrations are suggested starting amounts. Titration of the ZEB2 antibody may be required due to differences in protocols and secondary/substrate sensitivity.
Description:
Zinc finger E-box-binding homeobox 2, also known as SIP1 or Zinc finger homeobox 1B (ZFHX1B), is a protein that in humans is encoded by the ZEB2 gene. The gene is a member of the ZEB1/Drosophila Zfh1 family of two-handed zinc finger/homeodomain proteins and functions as a DNA-binding transcriptional repressor that interacts with activatedSMADs, the transducers ofTGF-betasignaling, and interacts with the nucleosome remodeling and histone deacetylation (NURD) complex. By radiation hybrid analysis, this gene is mapped to 2q22. It has been found that synthesis of ZEB2 was upregulated followingSNAI1expression in human cell lines, and the expression of SNAI1 in epithelial cells can trigger an epithelial-mesenchyme transition.
Format :
Antigen affinity purified
Formulation :
0.5mg/ml if reconstituted with 0.2ml sterile DI water
Gene ID #:
9839
Immunogen:
Human partial recombinant protein (AA 1-200) was used as the immunogen for this ZEB2 antibody.
Limitation:
This ZEB2 antibody is available for research use only.
Purity:
Antigen affinity
Species Reactivity :
Human