IFNAR1 Antibody / Interferon alpha receptor 1
Code | Size | Price |
---|
NSJ-RQ4481-100ul | 100ul | £535.00 |
Quantity:
Prices exclude any Taxes / VAT
Overview
Host Type: Rabbit
Antibody Isotype: Rabbit IgG
Antibody Clonality: Monoclonal
Antibody Clone: AF-9
Regulatory Status: RUO
Target Species: Human
Application: Western Blot (WB)
Storage:
Store the IFNAR1 antibody at -200.
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Further Information
Application Details :
Western blot: 1:500-1:2000
Application Note:
Optimal dilution of the IFNAR1 antibody should be determined by the researcher.
Description:
Component of the receptor for type I interferons, including interferons alpha, IFNB1 and IFNW1. Functions in general as heterodimer with IFNAR2. Type I interferon binding activates the JAK-STAT signaling cascade, and triggers tyrosine phosphorylation of a number of proteins including JAKs, TYK2, STAT proteins and the IFNR alpha- and beta- subunits themselves. Can form an active IFNB1 receptor by itself and activate a signaling cascade that does not involve activation of the JAK-STAT pathway (By similarity). [UniProt]
Format :
Purified
Formulation :
Antibody in PBS with 0.02% sodium azide and 50% glycerol
Immunogen:
A synthetic peptide from human Interferon Receptor alpha was used as the immunogen for the IFNAR1 antibody.
Limitation:
This IFNAR1 antibody is available for research use only.
Localization:
Cell membrane, Cytoplasm
Purity:
Protein A affinity
Species Reactivity :
Human
Uniprot #:
P17181