PLA2G7 Antibody / Lp-PLA2 / PAFAH

NSJ Bioreagents
Product Code: NSJ-RQ4597
Product Group: Primary Antibodies
Supplier: NSJ Bioreagents
CodeSizePrice
NSJ-RQ4597-100ug100ug£535.00
Quantity:
Prices exclude any Taxes / VAT

Overview

Host Type: Rabbit
Antibody Isotype: Rabbit IgG
Antibody Clonality: Polyclonal
Regulatory Status: RUO
Target Species: Human
Applications:
  • Enzyme-Linked Immunosorbent Assay (ELISA)
  • Western Blot (WB)
Storage:
After reconstitution, the PLA2G7 antibody can be stored for up to one month at 40. For long-term, aliquot and store at -200. Avoid repeated freezing and thawing.

Images

1 / 1
Western blot testing of human 1) Caco-2 and 2) SW620 lysate with PLA2G7 antibody at 0.5ug/ml. Predicted molecular weight ~50 kDa.

Western blot testing of human 1) Caco-2 and 2) SW620 lysate with PLA2G7 antibody at 0.5ug/ml. Predicted molecular weight ~50 kDa.

Further Information

Application Details :
Western blot: 0.5-1ug/ml,ELISA (Capture): 1-5ug/ml (human recombinant protein)
Application Note:
Optimal dilution of the PLA2G7 antibody should be determined by the researcher.
Description:
Lipoprotein-associated phospholipase A2 (Lp-PLA2), also known as platelet-activating factor acetylhydrolase (PAF-AH), is a phospholipase A2 enzyme that in humans is encoded by the PLA2G7 gene. Lp-PLA2 is a 45-50 kDa protein of 441 amino acids. It is one of several PAF acetylhydrolases. In the blood it travels mainly with low-density lipoprotein (LDL). Less than 20% is associated with high-density lipoprotein HDL. It is an enzyme produced by inflammatory cells and hydrolyzes oxidized phospholipids in LDL. Lp-PLA2 is platelet-activating factor (PAF) acetylhydrolase, a secreted enzyme that catalyzes the degradation of PAF to inactive products by hydrolysis of the acetyl group at the sn-2 position, producing the biologically inactive products LYSO-PAF and acetate.
Format :
Purified
Formulation :
0.5mg/ml if reconstituted with 0.2ml sterile DI water
Immunogen:
Amino acids A176-N415 from the human protein were used as the immunogen for the PLA2G7 antibody.
Limitation:
This PLA2G7 antibody is available for research use only.
Purity:
Antigen affinity purified
Species Reactivity :
Human
Uniprot #:
Q13093