CCL2 Antibody / MCP1

NSJ Bioreagents
Product Code: NSJ-RQ4664
Product Group: Primary Antibodies
Supplier: NSJ Bioreagents
CodeSizePrice
NSJ-RQ4664-100ug100ug£535.00
Quantity:
Prices exclude any Taxes / VAT

Overview

Host Type: Rabbit
Antibody Isotype: Rabbit IgG
Antibody Clonality: Polyclonal
Regulatory Status: RUO
Target Species: Rat
Applications:
  • Enzyme-Linked Immunosorbent Assay (ELISA)
  • Western Blot (WB)
Storage:
After reconstitution, the CCL2 antibody can be stored for up to one month at 40. For long-term, aliquot and store at -200. Avoid repeated freezing and thawing.

Images

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Western blot testing of rat pancreas with CCL2 antibody at 0.5ug/ml. Expected molecular weight ~11 kDa (precursor), ~9 kDa (mature).

Western blot testing of rat pancreas with CCL2 antibody at 0.5ug/ml. Expected molecular weight ~11 kDa (precursor), ~9 kDa (mature).

Further Information

Application Details :
Western blot: 0.5-1ug/ml,ELISA (Capture): 1-5ug/ml (recombinant rat protein)
Application Note:
Optimal dilution of the CCL2 antibody should be determined by the researcher.
Buffer:
Lyophilized from 1X PBS with 2% Trehalose
Description:
Monocyte chemoattractant protein-1 (MCP-1), a member of the chemokine (chemotactic cytokine) family, is a potent monocyte agonist that is upregulated by oxidized lipids. MCP-1 is also known as CCL2, SCYA2, MCAF. MCAF is a member of family of factors involved in immune and inflammatory responses. The amino acid sequence deduced from the nucleotide sequence reveals the primary structure of the MCAF precursor to be composed of a putative signal peptide sequence of 23 amino acid residues and a mature MCAF sequence of 76 amino acid residues. MCP-1 plays a unique and crucial role in the initiation of atherosclerosis and may provide a new therapeutic target in this disorder. Human MCP-1 is a 8.7KDa non-glycoprotein, consisting of 99 amino acids in precursor form and 76 amino acids in mature form.
Format :
Purified
Formulation :
0.5mg/ml if reconstituted with 0.2ml sterile DI water
Immunogen:
Amino acids Q24-R96 from the rat protein were used as the immunogen for the CCL2 antibody.
Limitation:
This CCL2 antibody is available for research use only.
Purity:
Antigen affinity purified
Species Reactivity :
Rat
Uniprot #:
P14844