Adipophilin Antibody [ADFP/1493]

ProSci
Product Code: PSI-33-587
Product Group: Primary Antibodies
Supplier: ProSci
CodeSizePrice
PSI-33-587-100ug100ug£765.00
Quantity:
Prices exclude any Taxes / VAT

Overview

Host Type: Mouse
Antibody Isotype: IgG2b, kappa
Antibody Clonality: Monoclonal
Antibody Clone: ADFP/1493
Regulatory Status: RUO
Target Species: Human
Applications:
  • Immunofluorescence (IF)
  • Immunohistochemistry- Paraffin Embedded (IHC-P)
Shipping:
blue ice
Storage:
Aliquot and Store at -20C. Avoid freez-thaw cycles.

Images

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IHC testing of FFPE human placental tissue with PLIN2 antibody (clone ADFP/1493). Required HIER: steam sections in pH6, 10mM citrate buffer for 10-20 min.

IHC testing of FFPE human placental tissue with PLIN2 antibody (clone ADFP/1493). Required HIER: steam sections in pH6, 10mM citrate buffer for 10-20 min.

Further Information

Additional Names:
Perilipin-2, Adipophilin, Adipose differentiation-related protein, ADRP, PLIN2, ADFP
Application Note:
ELISA: order formulation without BSA for coating

IHC (FFPE): 1-2 ug/ml

IF: 1-2 ug/ml

Titering of the PLIN2 antibody may be required for optimal performance.
Background:
Adipophilin, also called Perilipin 2, ADRP (Adipose differentiation related protein), and PLIN2, belongs to the perilipin family, members of which coat intracellular lipid storage droplets. This protein is associated with the lipid globule surface membrane material and maybe involved in development and maintenance of adipose tissue. It is not restricted to adipocytes as previously thought, but is found in a wide range of cultured cell lines, including fibroblasts, endothelial and epithelial cells, and tissues, such as lactating mammary gland, adrenal cortex, Sertoli and Leydig cells, and hepatocytes in alcoholic liver cirrhosis, suggesting that it may serve as a marker of lipid accumulation in diverse cell types and diseases.
Buffer:
PBS with 0.1 mg/ml BSA and 0.05% sodium azide
Concentration:
0.2 mg/mL
Conjugate:
Unconjugated
DISCLAIMER:
Optimal dilutions/concentrations should be determined by the end user. The information provided is a guideline for product use. This product is for research use only.
Immunogen:
A human partial recombinant protein was used as the immunogen for this PLIN2 antibody.
NCBI Gene ID #:
123
NCBI Official Name:
perilipin 2
NCBI Official Symbol:
PLIN2
NCBI Organism:
Homo sapiens
Physical State:
Liquid
Purification:
Protein G affinity chromatography
Research Area:
Cancer,Obesity,Signal Transduction
Swissprot #:
Q99541
User NOte:
Optimal dilutions for each application to be determined by the researcher