AMACR / p504S Antibody [AMACR/1723]

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ProSci
Product Code: PSI-33-611
Product Group: Primary Antibodies
Supplier: ProSci
CodeSizePrice
PSI-33-611-100ug100ug£765.00
Quantity:
Prices exclude any Taxes / VAT

Overview

Host Type: Mouse
Antibody Isotype: IgG
Antibody Clonality: Monoclonal
Antibody Clone: AMACR/1723
Regulatory Status: RUO
Target Species: Human
Applications:
  • Immunofluorescence (IF)
  • Immunohistochemistry- Paraffin Embedded (IHC-P)
  • Western Blot (WB)
Shipping:
blue ice
Storage:
Aliquot and Store at -20C. Avoid freez-thaw cycles.

Images

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IHC testing of FFPE human prostate carcinoma with AMACR antibody (clone AMACR/1723). HIER: steam sections in pH6, 10mM citrate buffer for 10-20 min.
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IHC testing of FFPE human prostate carcinoma with AMACR antibody (clone AMACR/1723). HIER: steam sections in pH6, 10mM citrate buffer for 10-20 min.

Documents

Further Information

Additional Names:
Alpha-methylacyl-CoA racemase, 2-methylacyl-CoA racemase, AMACR
Application Note:
Immunohistology (FFPE): 1-2 ug/ml for 30 minutes at RT

IF: 1-2 ug/ml

Optimal dilution of the AMACR antibody should be determined by the researcher.
Background:
AMACR, also known as p504S is an enzyme that is involved in bile acid biosynthesis and beta-oxidation of branched-chain fatty acids. It is expressed in cells of premalignant high-grade prostatic intraepithelial neoplasia (HGPIN) and prostate adenocarcinoma. The majority of the carcinoma cells show a distinct granular cytoplasmic staining reaction. AMACR is present at low or undetectable levels in glandular epithelial cells of normal prostate and benign prostatic hyperplasia. A spotty granular cytoplasmic staining is seen in a few cells of the benign glands.
Buffer:
PBS with 0.1 mg/ml BSA and 0.05% sodium azide
Concentration:
0.2 mg/mL
Conjugate:
Unconjugated
DISCLAIMER:
Optimal dilutions/concentrations should be determined by the end user. The information provided is a guideline for product use. This product is for research use only.
Immunogen:
A recombinant human protein was used as the immunogen for the AMACR antibody.
NCBI Gene ID #:
23600
NCBI Official Name:
alpha-methylacyl-CoA racemase
NCBI Official Symbol:
AMACR
NCBI Organism:
Homo sapiens
Physical State:
Liquid
Purification:
Protein G affinity chromatography
Research Area:
Cancer,Cell Cycle,Obesity,Signal Transduction
Swissprot #:
Q9UHK6
User NOte:
Optimal dilutions for each application to be determined by the researcher