ATG4B Antibody

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ProSci
Product Code: PSI-33-063
Product Group: Primary Antibodies
Supplier: ProSci
CodeSizePrice
PSI-33-063-100ug100ug£662.00
Quantity:
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Overview

Host Type: Rabbit
Antibody Isotype: IgG
Antibody Clonality: Polyclonal
Regulatory Status: RUO
Target Species:
  • Human
  • Mouse
Application: Western Blot (WB)
Shipping:
blue ice
Storage:
Aliquot and Store at -20C. Avoid freez-thaw cycles.

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Western blot testing of human samples with ATG4B antibody at 4ug/ml.
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Western blot testing of human samples with ATG4B antibody at 4ug/ml.

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Further Information

Additional Names:
Autophagy related 4B cysteine peptidase, APG4B, APG4-B, AUTL1
Application Note:
Western blot: 4-8 ug/ml

Provided assay concentrations are suggestions only, ATG4B antibody titration may be required for optimal results.
Background:
Autophagy is the cellular mechanism of degradation and turnover of unnecessary or dysfunctional cellular components. The unneeded components are engulfed in vesicles called autophagosomes, where they are broken down and recycled. The ?autophagy-related gene? ATG4B is a regulator of autophagasome maturation. The microtubule-associated protein LC3-I is lipidated (called LC3-II in its lipidated state) and recruited to the autophagosomal membrane where it is of vital importance in the maturation of autophagosomes. ATG4B regulates LC3-II availability by modulating LC3-I lipidation.
Buffer:
PBS with 0.1 mg/ml BSA and 0.05% sodium azide
Concentration:
0.5 mg/mL
Conjugate:
Unconjugated
DISCLAIMER:
Optimal dilutions/concentrations should be determined by the end user. The information provided is a guideline for product use. This product is for research use only.
Immunogen:
A recombinant protein fragment from the C-terminal region of ATG4B was used as the immunogen for this antibody.
NCBI Gene ID #:
23192
NCBI Official Name:
autophagy related 4B, cysteine peptidase
NCBI Official Symbol:
ATG4B
NCBI Organism:
Homo sapiens
Physical State:
Liquid
Purification:
Protein A affinity chromatography
Research Area:
Autophagy
Swissprot #:
Q9Y4P1
User NOte:
Optimal dilutions for each application to be determined by the researcher