Bax Antibody [2D2]
| Code | Size | Price |
|---|
| PSI-99-622-0.1mg | 0.1mg | £505.00 |
Quantity:
Prices exclude any Taxes / VAT
Overview
Host Type: Mouse
Antibody Isotype: IgG1
Antibody Clonality: Monoclonal
Antibody Clone: [2D2]
Regulatory Status: RUO
Target Species:
- Bovine (Cattle)
- Canine (dog)
- Human
- Monkey
Application: Flow Cytometry
Shipping:
blue ice
Storage:
Store vial at 2-8˚C
Documents
Further Information
Additional Names:
Apoptosis regulator BAX, BCL2 associated X protein
Application Note:
Bax Antibody [2D2] for use in flow cytometry, immunohistochemistry / immunocytochemistry, western blotting, immunoprecipitation, purification, and neutralization assays.
Background:
Bax is a 20-22 kDa member of the Bcl-2 family of proteins involved in regulation of programmed cell death, or apoptosis. In murine thymocytes, it is expressed primarily as a cytoplasmic protein. Over-expression of Bax promotes apoptosis by formation of homodimers and through heterodimerization with Bcl-2, an inhibitor of apoptosis. The monoclonal antibody 2D2 reacts with an N-terminal epitope between amino acids 3-16 of human Bax. It can bind both soluble and detergent-altered forms of Bax as well as Bax-Bcl-2 and Bax-Bcl-xL heterodimers.
Buffer:
Supplied in borate buffered saline, pH 8.2; No preservatives or amine-containing buffer salts added
Concentration:
0.1 mg/mL
Conjugate:
Unconjugated
DISCLAIMER:
Optimal dilutions/concentrations should be determined by the end user. The information provided is a guideline for product use. This product is for research use only.
Immunogen:
Human Bax peptide (a.a. 3-16)
NCBI Gene ID #:
581
NCBI Official Name:
BCL2-associated X protein
NCBI Official Symbol:
BAX
NCBI Organism:
Homo sapiens
Physical State:
Liquid
Protein Accession #:
Q07812
Research Area:
Membrane,Cell Cycle,Cancer,Apoptosis
SPECIFICITY:
Bax
Swissprot #:
Q07812
User NOte:
Optimal dilutions for each application to be determined by the researcher.