Bcl-2 Antibody [10C4]
| Code | Size | Price |
|---|
| PSI-99-624-0.1mg | 0.1mg | £505.00 |
Quantity:
Prices exclude any Taxes / VAT
Overview
Host Type: Mouse
Antibody Isotype: IgG1
Antibody Clonality: Monoclonal
Antibody Clone: [10C4]
Regulatory Status: RUO
Target Species:
- Mouse
- Rat
Application: Flow Cytometry
Shipping:
blue ice
Storage:
Store vial at 2-8˚C
Documents
Further Information
Additional Names:
B cell leukemia 2
Application Note:
Bcl-2 Antibody [10C4] for use in flow cytometry, immunohistochemistry / immunocytochemistry, western blotting, and immunoprecipitation assays.
Background:
Bcl-2 is a 26 kDa member of the family of proteins involved in regulation of programmed cell death, or apoptosis. It is expressed in a variety of both normal and neoplastic tissues and appears to be membrane-bound since it is detectable in crude membrane and nuclear fractions, but not in the soluble fraction of cell lysates. Overexpression of Bcl-2 can prevent apoptosis, while formation of heterodimers with Bax, another Bcl-2-related protein, inhibits Bcl-2?s ability to promote cell survival.
Buffer:
Supplied in borate buffered saline, pH 8.2; No preservatives or amine-containing buffer salts added
Concentration:
0.1 mg/mL
Conjugate:
Unconjugated
DISCLAIMER:
Optimal dilutions/concentrations should be determined by the end user. The information provided is a guideline for product use. This product is for research use only.
Immunogen:
Murine Bcl-2 peptide (a.a. 61-76)
NCBI Gene ID #:
12043/24224
NCBI Official Name:
B cell leukemia/lymphoma 2
NCBI Official Symbol:
Bcl2
NCBI Organism:
Mus musculus
Physical State:
Liquid
Protein Accession #:
P10417
Research Area:
Cancer,Obesity,Signal Transduction
SPECIFICITY:
Bcl-2
Swissprot #:
P10417
User NOte:
Optimal dilutions for each application to be determined by the researcher.