Bcl-xL Antibody [7B2.5] (FITC)
| Code | Size | Price |
|---|
| PSI-99-617-0.1mg | 0.1mg | £729.00 |
Quantity:
Prices exclude any Taxes / VAT
Overview
Host Type: Mouse
Antibody Isotype: IgG3
Antibody Clonality: Monoclonal
Antibody Clone: [7B2.5]
Regulatory Status: RUO
Target Species:
- Human
- Mouse
- Rat
Application: Flow Cytometry
Shipping:
blue ice
Storage:
Store vial at 2-8˚C
Documents
Further Information
Additional Names:
Apoptosis regulator Bcl-X, Bcl-2-like 1 protein, BCL2L1
Application Note:
Bcl-xL Antibody [7B2.5] for use in flow cytometry, immunohistochemistry / immunocytochemistry, and western blotting assays.
Background:
Bcl-xL is a 29 kDa member of the Bcl-2 family of proteins involved in regulation of programmed cell death, or apoptosis. It is found in both soluble and membrane fractions of cellular lysates. Like Bcl-2, Bcl-xL has been demonstrated to block apoptosis which is induced by a variety of stimuli and, under certain conditions, offers greater protection against apoptosis than Bcl-2. While formation of heterodimers with the apoptosis-enhancing protein, Bax does not block the apoptosis-suppressing property of Bcl-xL, heterodimerization with Bad effectively inhibits the protective function of Bcl-xL.
Buffer:
Supplied in PBS/NaN3
Concentration:
0.1 mg/mL
Conjugate:
FITC
DISCLAIMER:
Optimal dilutions/concentrations should be determined by the end user. The information provided is a guideline for product use. This product is for research use only.
Immunogen:
Recombinant human Bcl-xS
NCBI Gene ID #:
598
NCBI Official Name:
BCL2-like 1
NCBI Official Symbol:
BCL2L1
NCBI Organism:
Homo sapiens
Physical State:
Liquid
Protein Accession #:
Q07817
Research Area:
Transcription,Cancer
SPECIFICITY:
Bcl-xL
Swissprot #:
Q07817
User NOte:
Optimal dilutions for each application to be determined by the researcher.