CD1.1 Antibody [CB3]
| Code | Size | Price |
|---|
| PSI-99-333-0.5mg | 0.5mg | £597.00 |
Quantity:
Prices exclude any Taxes / VAT
Overview
Host Type: Mouse
Antibody Isotype: IgG1
Antibody Clonality: Monoclonal
Antibody Clone: [CB3]
Regulatory Status: RUO
Target Species: Chicken (Gallus)
Application: Flow Cytometry
Shipping:
blue ice
Storage:
Store vial at 2-8˚C
Documents
Further Information
Application Note:
CD1.1 Antibody [CB3] for use in flow cytometry, immunohistochemistry / immunocytochemistry, and immunoprecipitation assays.
Background:
CD1 molecules, like MHC I and II, play an important role in the immune system by presenting lipid, glycolipid and lipopeptide antigen to T and NKT cells. The chicken CD1 gene is located in the chicken MHC B locus and has an important implication for the primordial MHC gene evolution. Two proteins have been identified - CD1.1 and CD1.2. Analysis of RNA from blood cells showed that both genes are expressed in Bu-1+ cells and CD8alpha+ cells. CD1.2 is expressed in TCRgammadelta cells but is nearly undetectable in TCRalphabeta. The monoclonal antibody CB3 antibody can identify cells of the B cell lineage and recognizes CD1.1 but not CD1.2 on the surface of transfected mammalian cells.
Buffer:
Supplied in borate buffered saline, pH 8.2; No preservatives or amine-containing buffer salts added
Concentration:
0.5 mg/mL
Conjugate:
Unconjugated
DISCLAIMER:
Optimal dilutions/concentrations should be determined by the end user. The information provided is a guideline for product use. This product is for research use only.
Immunogen:
Lymphocytes from the bursa of Fabricius of outbred chickens
NCBI Gene ID #:
425801/425802
NCBI Official Name:
CD1c molecule
NCBI Official Symbol:
CD1C
NCBI Organism:
Gallus gallus
Physical State:
Liquid
Research Area:
Immunology
SPECIFICITY:
CD1.1
User NOte:
Optimal dilutions for each application to be determined by the researcher.