CD105 Antibody [MJ7/18]
| Code | Size | Price |
|---|
| PSI-99-004-0.5mg | 0.5mg | £560.00 |
Quantity:
Prices exclude any Taxes / VAT
Overview
Host Type: Rat
Antibody Isotype: IgG2a
Antibody Clonality: Monoclonal
Antibody Clone: [MJ7/18]
Regulatory Status: RUO
Target Species: Mouse
Application: Immunohistochemistry- Frozen Section (IHC-F)
Shipping:
blue ice
Storage:
Store vial at 2-8˚C
Documents
Further Information
Additional Names:
Endoglin
Application Note:
CD105 Antibody [MJ7/18] for use in flow cytometry, immunohistochemistry, western blotting, immunoprecipitation, and separation assays.
Background:
CD105, also known as endoglin, is a disulfide-linked type II transmembrane homodimer that is predominantly expressed on vascular endothelial cells. It is also found on pre-erythroblasts, macrophages, and lymphoid and myeloid leukemic cells. Both mouse and human CD105 exhibit >70% sequence homology in their cytoplasmic domains with type III transforming growth factor beta (TGFbeta) receptor. CD105 has been shown to be one of several receptors for the various isoforms of TGFbeta which in turn is one of a family of proteins involved in regulation of cell differentiation, migration of cells, and control of the immune response.
Buffer:
Supplied in borate buffered saline, pH 8.2; No preservatives or amine-containing buffer salts added
Concentration:
0.5 mg/mL
Conjugate:
Unconjugated
DISCLAIMER:
Optimal dilutions/concentrations should be determined by the end user. The information provided is a guideline for product use. This product is for research use only.
Immunogen:
Inflamed mouse skin
NCBI Gene ID #:
13805
NCBI Official Name:
endoglin
NCBI Official Symbol:
Eng
NCBI Organism:
Mus musculus
Physical State:
Liquid
Protein Accession #:
Q63961
Research Area:
Stem Cell
SPECIFICITY:
CD105
Swissprot #:
Q63961
User NOte:
Optimal dilutions for each application to be determined by the researcher.