CD107a Antibody [1D4B] (APC)
| Code | Size | Price |
|---|
| PSI-99-111-0.1mg | 0.1mg | £524.00 |
Quantity:
Prices exclude any Taxes / VAT
Overview
Host Type: Rat
Antibody Isotype: IgG2a
Antibody Clonality: Monoclonal
Antibody Clone: [1D4B]
Regulatory Status: RUO
Target Species: Mouse
Applications:
- Blocking
- Immunocytochemistry (ICC)
- Immunohistochemistry- Frozen Section (IHC-F)
- Immunoprecipitation (IP)
Shipping:
blue ice
Storage:
Store vial at 2-8˚C
Documents
Further Information
Additional Names:
LAMP-1, lysosomal-associated membrane protein 1
Application Note:
CD107a Antibody [1D4B] for use in flow cytometry assays.
Background:
CD107a, also known as lysosomal-associated membrane protein 1 (LAMP-1), is a heavily glycosylated type I transmembrane protein that constitutes one of the two major sialoglycoproteins on lysosomal membranes that can be used to distinguish lysosomes from other organelles. It is a ligand for galaptin, an S-type lectin present in extracellular matrix, through its recognition of acetyllactosamine oligosaccharide chains and is a ligand for E-selectin-mediated cell adhesion. CD107a is principally expressed in epithelial cells and macrophages in a variety of organs in normal and beige mutant mice. It may function in protecting the inner surface of the lysosomal membrane by forming a barrier to lysosomal hydrolases.
Buffer:
Supplied in PBS/NaN3 and a stabilizing agent
Concentration:
0.1 mg/mL
Conjugate:
APC
DISCLAIMER:
Optimal dilutions/concentrations should be determined by the end user. The information provided is a guideline for product use. This product is for research use only.
Immunogen:
Plasma membrane fraction of mouse embryo NIH/3T3 cell line
NCBI Gene ID #:
16783
NCBI Official Name:
lysosomal-associated membrane protein 1
NCBI Official Symbol:
Lamp1
NCBI Organism:
Mus musculus
Physical State:
Liquid
Protein Accession #:
P11438
Research Area:
Innate Immunity
SPECIFICITY:
CD107a
Swissprot #:
P11438
User NOte:
Optimal dilutions for each application to be determined by the researcher.