CD11b Antibody [3A33]
| Code | Size | Price |
|---|
| PSI-98-632-0.5mg | 0.5mg | £469.00 |
Quantity:
Prices exclude any Taxes / VAT
Overview
Host Type: Rat
Antibody Isotype: IgG2a
Antibody Clonality: Monoclonal
Antibody Clone: [3A33]
Regulatory Status: RUO
Target Species: Mouse
Applications:
- Immunocytochemistry (ICC)
- Immunohistochemistry- Frozen Section (IHC-F)
Shipping:
blue ice
Storage:
Store vial at 2-8˚C
Documents
Further Information
Additional Names:
Integrin alphaM, Mac-1alpha, Mac-1, Mo1, CR3, C3biR
Application Note:
CD11b Antibody [3A33] for use in flow cytometry, immunohistochemistry / immunocytochemistry, immunoprecipitation, and blocking assays.
Background:
CD11b (integrin alphaM subunit) combines with CD18 (integrin beta2 subunit) to form the integrin Mac-1, also known as complement receptor 3 (CR3), which mediates adhesion to C3bi and ICAM-1 (CD54). Mac-1 is expressed at varying levels on granulocytes, macrophages, dendritic cells, NK cells, and B-1 cells in the peritoneal and pleural cavities. In addition to its role in binding C3bi on opsonized targets and mediation of the subsequent ingestion process, Mac-1 is important as an adhesion molecule in the transendothelial migration of monocytes and neutrophils.
Buffer:
Supplied in borate buffered saline, pH 8.2; No preservatives or amine-containing buffer salts added
Concentration:
0.5 mg/mL
Conjugate:
Unconjugated
DISCLAIMER:
Optimal dilutions/concentrations should be determined by the end user. The information provided is a guideline for product use. This product is for research use only.
Immunogen:
Peritoneal macrophages from B6D2 hybrid mice
NCBI Gene ID #:
16409
NCBI Official Name:
Integrin alpha M
NCBI Official Symbol:
Itgam
NCBI Organism:
Mus musculus
Physical State:
Liquid
Protein Accession #:
P05555
Research Area:
Immunology,Neuroscience,Signal Transduction
SPECIFICITY:
CD11b
Swissprot #:
P05555
User NOte:
Optimal dilutions for each application to be determined by the researcher.