CD11c Antibody [HC1/1]
| Code | Size | Price |
|---|
| PSI-33-158-100ug | 100ug | £765.00 |
Quantity:
Prices exclude any Taxes / VAT
Overview
Host Type: Mouse
Antibody Isotype: IgG1, kappa
Antibody Clonality: Monoclonal
Antibody Clone: HC1/1
Regulatory Status: RUO
Target Species: Human
Application: Immunofluorescence (IF)
Shipping:
blue ice
Storage:
Aliquot and Store at -20C. Avoid freez-thaw cycles.
Documents
Further Information
Additional Names:
Integrin alpha-X, CD11 antigen-like family member C, Leu M5, Leukocyte adhesion glycoprotein p150,95 alpha chain, Leukocyte adhesion receptor p150, CD11c, ITGAX, CD11C
Application Note:
Flow Cytometry: 0.5-1 ug/million cells
IF: 0.5-1 ug/ml
Functional Activity (Blocking): order BSA/azide free format
The concentration stated for each application is a general starting point. Variations in protocols, secondaries and substrates may require the CD11c antibody to be titered up or down for optimal performance.
IF: 0.5-1 ug/ml
Functional Activity (Blocking): order BSA/azide free format
The concentration stated for each application is a general starting point. Variations in protocols, secondaries and substrates may require the CD11c antibody to be titered up or down for optimal performance.
Background:
CD11c, also known as Integrin alpha X (complement component 3 receptor 4 subunit) (ITGAX), is a type I transmembrane protein found at high levels on most human dendritic cells, but also on monocytes, macrophages, neutrophils, and some B cells that induces cellular activation and helps trigger neutrophil respiratory burst; expressed in hairy cell leukemias, acute non-lymphocytic leukemias, and some B-cell chronic lymphocytic leukemias.
Buffer:
PBS with 0.1 mg/ml BSA and 0.05% sodium azide
Concentration:
0.2 mg/mL
Conjugate:
Unconjugated
DISCLAIMER:
Optimal dilutions/concentrations should be determined by the end user. The information provided is a guideline for product use. This product is for research use only.
Immunogen:
Human monocytic U937 phorbol ester-treated cells were used as the immunogen for this CD11c antibody.
NCBI Gene ID #:
3687
NCBI Official Name:
integrin, alpha X (complement component 3 receptor 4 subunit)
NCBI Official Symbol:
ITGAX
NCBI Organism:
Homo sapiens
Physical State:
Liquid
Purification:
Protein G affinity chromatography
Research Area:
Immunology,Signal Transduction
Swissprot #:
P20702
User NOte:
Optimal dilutions for each application to be determined by the researcher